Ketoconazole reaches the surface of the skin through normal blood circulation, sweat and sebum (skin oils). Very high concentrations of the drug develop within the skin, so it is effective in treating superficial fungal infections. The oral dose of Ketoconazole in adults is 200 to 400 mg daily, taken for two to eight weeks (a single dose may be effective for pityriasis versicolor). Nail infections are treated for up to twelve months. The dose in children is usually 50 mg per day for those weighing less than 20 kg and 100mg daily for those 20-40 kg. The oral medication is somewhat better absorbed when it is taken with a fatty meal or acidic drink (e.g. orange juice). It is bound to proteins such as albumin in the circulating blood and is widely distributed in body tissues. It takes three to ten hours for half of the medication to be cleared from the blood stream. The rest is eliminated in faeces and urine either unchanged or after conversion by the liver into inactive compounds.
Other names for this medication:
Ketoconazole,
Nizoral,
Akorazol,
Arcolan,
Arcolane,
Asquam,
Biogel,
Clarazole,
Conazol,
Daktagold,
Daktarin,
Dezor,
Diazon,
Dikoven,
Eumicel,
Extina,
Funginoc,
Fungoral,
Ilgem,
Kenazol,
Kenazole,
Ketazol,
Ketokonazol,
Ketolef,
Ketovid,
Ketozal,
Liondox,
Lizovag,
Micoral,
Micosin,
Muzoral,
Mycoderm,
Noell,
Orifungal,
Oronazol,
Panfungol,
Perative,
Phytoral,
Pristinex,
Tiniazol,
Tinuvin,
Xolegel,
Yucomy,
Zoloral,
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Clopilet,
Diazole,
Agrocin,
Omicap,
Calutide,
Quetiapin,
Calton,
Flutec,
Femalefil,
Dalfaz,
Infex,
Lamolep,
Novotrim,
Xorox,
Capro,
Prochlorperazine,
Mazepine,
Ulcozol,
Pandev,
Seroquel,
Levocin,
Efexor,
Llanol,
Clavumox,
Mecir,
Macrobid,
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