Candistat is active in general against various types of fungi, including yeasts, moulds, and dimorphic fungi. Among these are, Candida spp., Cryptococcus neoformans, Aspergillus spp., Pseudallescheria boydii, Sporothrix schenckii, Histoplasma capsulatum, Blastomyces dermatitidis, Coccidioides immitis, Paracoccidioides brasiliensis, Penicillium marneffei and dermatophytes. Resistance to Candistat is detectable among the types of fungi noted above as well as others. Its activity against some (but not all!) fluconazole-resistant C. krusei and C. glabrata isolates is noteworthy. However, cross-resistance among azoles is not uncommon and a subset of fluconazole-resistant isolates generate high Candistat MICs as well. Aspergillus fumigatus isolates that are resistant to Candistat in vivo and generate high MICs in vitro have already been identified. Activity of Candistat is limited against Fusarium spp. [119] and zygomycetes group of fungi.
Other names for this medication:
Itraconazole,
Sporanox,
Fulcover,
Icoz,
Candistat,
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