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Deetor (Dutasteride)

Deetor is a synthetic 4-azasteroid compound. Deetor competitively and specifically binds to isoenzymes 1 and 2 of 5 alpha-reductase, forming stable enzyme complexes and inhibiting the conversion of testosterone to 5 alpha-dihydrotestosterone (DHT); the reduction in DHT activity may mitigate or prevent enlargement of the prostate gland. The type 2 5 alpha-reductase isoenzyme is primarily active in the reproductive tissues, while the type 1 isoenzyme is also active in skin and the liver.

Other names for this medication:
Dutasteride, Deetor, Duodart, Duprost, Dutagen, Dutas, Dutasterida, Dute, Veltride,

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We have addressed the question of the requirement for insulin/IGF-1 also observed in many cell culture systems in the physiologically relevant system of primary cultures of dog thyroid epithelial cells stimulated by TSH, which exerts its mitogenic activity only via cAMP. We divided the participants into two subgroups: the 2-h PG-side group and the FPG-side from the regression line, and examined the relationships between 2-h PG-FPG and factors responsible for elevation of plasma glucose levels. Comparative transcriptome profiling of developing caryopses from two rice cultivars with differential dormancy.

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A trial of patients admitted for pre-surgical studies permitted verification of the efficacy and safety of higher doses (3,600 mg/day) than those previously used (800-2,400 mg/day). In this study, in vivo toxic effects of DA were investigated on fish Oreochromis niloticus (Fam: Cichlidae), using oxidative stress biomarkers. The peculiarity of the growth of pentacene on PEDOT:PSS is due to the fact that the substrate does not offer any template for the nucleated films and thus exerts a lateral order toward the crystal structure arrangement. DN-Dmp53-dependent lifespan extension is accompanied by reduction of Drosophila insulin-like peptide 2 (dILP2) mRNA levels and reduced insulin signaling (IIS) in the fat body, which suggests that Dmp53 may affect lifespan by modulating insulin signaling in the fly. Results revealed that post-pandemic influenza seasons in Macedonia were rather different.

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Many of those who gathered at the prestigious Nurse 90 Awards dinner in London last week were well-known figures whose faces are familiar to most of the profession. The role of these seizure-induced newborn neurons in the process of epileptogenesis remains largely unknown. This study is aimed to evaluate the etiology, clinical manifestations and therapeutic outcome in patients with palpable purpura and to assess the relevance of IgA deposits in these patients. Tissue adhesives for traumatic lacerations in children and adults.

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Tongue biopsy led to the diagnosis of amyloidosis, serum immunofixation identified AL amyloidosis and a kappa light chain gammopathy resulting from multiple myeloma as the underlying cause. Secondary endpoints were to examine the effects of androgen therapy on hematocrit and erythropoietin (EPO) dose. Aspirin-intolerant chronic urticaria exacerbated by cutaneous application of a ketoprofen poultice. Amplification of platelet response during acute inflammation in rats.

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In addition, word finding difficulties have been found to be less severe in connected speech than picture naming. Neuronal response sensitivity to bidirectional off-vertical axis rotations: a dimension of imbalance in the bilateral vestibular nuclei of cats after unilateral labyrinthectomy.

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Comparative Analysis of Methods for Detecting Isocitrate Dehydrogenase 1 and 2 Mutations and Their Metabolic Consequence, 2-Hydroxyglutarate, in Different Neoplasms. The effects of troglitazone, PDT, and troglitazone in combination with PDT on cell viability and apoptosis were assessed in DLD-1 cells. Children with indwelling central venous catheters are at risk of embolisation of catheter fragments.

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Percutaneous endoscopic gastrostomy (PEG) is preferred when prolonged treatment is envisaged. The effect of autonomic perturbation (AP) on the central nervous system functioning is still largely unknown. Clinical trials have been undertaken in infants with rapidly progressive LAL-D and in children and adults with later-onset LAL-D.

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Escalation using oral agents rather than insulin is associated with better quality of life and lower costs, though these relationships may not be causal. Psychoanalytic-interactional therapy in patients with preoedipal disorder components Neurobiological data suggest that estrogen may facilitate drug taking by interacting with reward- and stress-related systems. In addition to its potential biologic effects, acidified water might interact with the water-delivery system, leading to the leaching of heavy metals into the drinking water.

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Six of these culture-positive sheep had no macroscopic signs of paratuberculosis at necropsy. They were tested for their inhibitory activity on photosynthetic electron transport (PET) in spinach (Spinacia oleracea L.) chloroplasts. UKMP-5M isolate was shown to detoxify cyanide successfully, suggesting the presence of an intrinsic property in the bacterium which required no prior cyanide exposure for induction of this property. Scientometric analysis and mapping of 20 years of glaucoma research. Purification and properties of ornithine carbamoyltransferase from loggerhead turtle liver.

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Our findings indicate that thrombin-induced Ang-2 expression in LVAD patients leads to increased angiogenesis in vitro and may be associated with higher nonsurgical bleeding events. During inflammation, the resulting oxidative stress can damage surrounding host tissue, forming protein-carbonyls. No significant correlation was detected between 2D:4D or Sal/T and the playing position of players.

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The dissemination of Rift Valley fever (RVF) virus in females of the epidemic vector Culex pipiens was studied immunocytochemically. Measurements of morning cortisol at 1-2 weeks and DT within 6 months after TSS. An interstitial deletion, 17cen----q11.2 (or q12), and a small extra chromosome was found in a sporadic case of von Recklinghausen neurofibromatosis (NF1). A Randomized Multicenter Clinical Trial of Ultrathin Descemet Stripping Automated Endothelial Keratoplasty (DSAEK) versus DSAEK.

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MR imaging of four surgically confirmed cases of intraspinal synovial cysts revealed subtle signal changes compared with CSF. We present the first case to be published, of an intracranial optic nerve cavernous malformation with a contiguous canalicular component that was totally and successfully removed through a microsurgical pterional approach with excellent clinical outcome. To expand the quantitative, systems level understanding and foster the expansion of the biotechnological applications of the filamentous bacteriophage M13, we have unified the accumulated quantitative information on M13 biology into a genetically-structured, experimentally-based computational simulation of the entire phage life cycle. After adjusting for comorbidity, the number of mood, anxiety, impulse-control, and substance disorders remained significantly associated with arthritis onset showing odds ratios (ORs) ranging from 1.2 to 1.4.

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Serum calcitonin was 1,453 pg/ml and carcinoembryonic antigen was 201 ng/ml. Many nerve fibers within the tissue exhibited clear immunoreactivity including motor endplates on striated muscle, autonomic fibers innervating blood vessels or glands, and sensory fibers innervating muscles or the lingual epithelium including taste buds. Femoroacetabular impingement syndrome (FAI) represents a mechanical conflict between acetabulum and proximal part of the femur. This study reports that the bone dusts, usually discarded as surgical wastes during transforaminal lumbar interbody fusion procedure (TLIF procedure), yielded cells which had the characteristics of mesenchymal stem cells (MSCs) in vitro.

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In addition, mass spectrometry indicates that arginine residues in RG repeats at the N-termini of Miwi and Mili are methylated in vivo. Prevention aims at changing and then sustaining specific patterns of behavior and thus addresses the individual acting as an autonomous, responsible person.

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For five small structurally dissimilar proteins, we find that we can separate native-like structures from the vast majority of non-native folds by using only simple structural and energetic criteria. In addition to endosymbiotic gene transfer, the acquisition of a protein import apparatus and the coordination of gene expression between host and endosymbiont genomes, the establishment of a metabolic connection was crucial for a functional endosymbiosis.

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There are fundamental issues to address within the context of healthcare provision that are of direct relevance to improving services for people with intellectual disabilities with regard to their empowerment and the facilitation of care. We retrospectively analysed the pleural fluid and serum protein, lactate dehydrogenase and albumin concentrations from 364 cardiac effusions and 102 HH. In the following, we describe an alternative, off-pump technique that combines a median sternotomy with limited dissection of the right-heart with a left anterolateral thoracotomy.

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These findings on ARID1A and its role of tumor suppression contribute to understanding the mechanism of cancer development and developing new therapy for cancer.It is introduced in the review that ARID1A basic characteristic, related to cancer development, and biological role for full understanding of ARID1A. Along with plants, information was also collected on plant parts used, formulations, and dosages. Morphological spectrum of peripheral nerve sheath tumors: An insight into World Health Organization 2013 classification. This paper describes tests that were carried out to model the stress relaxation behaviour of polymethylmethacrylate (PMMA) bone cement. Our results add weight to the case that total bans on shark fishing are a better conservation approach for sharks than marine protected area networks.

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The biological consequences of failing to temporally regulate HR via Rhp54 degradation are seen in haploid cells only in the absence of antirecombinase Srs2 function and are more extensive in diploid cells, which become sensitive to a range of DNA-damaging agents, including hydroxyurea, methyl methanesulfonate, bleomycin, and UV. ROC curve analysis demonstrated apolipoprotein E and A-I and hemopexin as efficient predictors for meningiomas. To evaluate further the relevance of SR-BI in the enterohepatic circulation of cholesterol and bile salts, we studied biliary lipid secretion, hepatic sterol content and synthesis, bile acid metabolism, fecal neutral sterol excretion, and intestinal cholesterol absorption in SR-BI knockout mice.

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We used a novel pharmacological assay, based on SDS-stable interaction between (125)I-echistatin and RGD-dependent integrins, to evaluate the specificity of several RGD compounds on integrins present on rat cardiac fibroblasts and human skin fibroblasts. The patient underwent a successful left thoracotomy with a lobectomy of the left lower lobe of the lung 5 days after the biopsy and recovered uneventfully.

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Flibanserin showed a moderate benefit in terms of frequency of sex and patient satisfaction. Medical workforce shortages in Australia have led to increasing reliance on overseas-trained doctors (OTDs) to work in general practice in areas of need, particularly in rural areas. This CbKST approach will provide clinicians who undertake medical procedures to better understand their own performance, and to improve over time.

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Gene expression profiles represent a critical case study since they suffer from the curse of dimensionality problem that negatively reflects on the reliability of both traditional rejection models and also more recent approaches such as one-class classifiers. This goal of this study was to understand the patterns of expressed emotions (EEs) in adolescent eating disorders.

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Regeneration of the epidermis seems to be facilitated by anchorage of the regenerating cells in the fibrillar network as well as by formation of the basement membrane, which probably is produced by the squamous and fibroblastic cells. Factors underlying a possible excess of amyotrophic lateral sclerosis (ALS) among military veterans remain unidentified. Behavorial analyses show that TRAF4-deficient mice (TRAF4-KO) exhibit altered locomotion coordination typical of ataxia. However, their capability to remove seeds has been reported only once. We investigated whether the same factors pertain in Suhum-Kraboa-Coaltar (SKC) and Akuapem South (AS) Districts in Ghana which previously were not endemic for BU.

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This retrospective study assesses the outcomes and patterns of failure in patients with squamous cell carcinoma metastatic to cervical lymph nodes from an unknown primary site treated with combined surgery and postoperative radiotherapy. We conducted a single-blind, randomized controlled trial of MBP versus NaP in women undergoing minimally invasive pelvic reconstructive surgery. Distal clavicle fracture mimicking type IV acromioclavicular joint injury in the skeletally immature athlete. Insulin inhibits delta-aminolevulinate synthase gene expression in rat hepatocytes and human hepatoma cells. Interviews were structured to identify themes within a health systems approach.

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Intrathecal Opioid-Induced Hypothermia Following Subarachnoid Block With Morphine Injection for Elective Cesarean Delivery: A Case Report. Some Anomalies in the Morphology of Plasmodium Vivax Occurring in a Newborn Baby.

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Cervical length was measured by transvaginal sonography at 23 (range 22-24) weeks of gestation in 43 triplet pregnancies. The patient had normal velopharangeal competence but absence of tongue which was replaced by a small mucus membrane projection near the floor of oropharangeal isthmus. It is characterized by painful progressive necrosis of the wound margins. After the combined implementation of 4 overlapping bare stents and a stent graft, TAAA was excluded while the 4 visceral arteries were reserved. Tandem duplication and block duplication were found among the Ariadne B and Plant IIC group of soybean RBR genes.

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Here we describe the computational steps required to process PcG ChIP-seq data, including alignment, peak calling, and downstream analysis. Data characterizing tensile behavior of cenosphere/HDPE syntactic foam.

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There was no decrease in the number of administrative controls generated by the intervention group. Modifiers of stress related to timing of diagnosis in parents of children with complex congenital heart disease. Because of the high density of immobilized RLKs, ligand-receptor interaction can be visualized at high sensitivity using fluorescent-labeled ligands under the confocal laser scanning microscope. Thoracic duct ligation and partial pericardectomy remain the preferred treatment for chylopericardium.

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Vascular dementia: a contemporary review of epidemiology, diagnosis, prevention, and treatment. We defined 44 cities based on region/postal code and settlement size. Enzyme linked immunosorbent assays (ELISAs) are employed for the detection and quantification of antigens from biological sources such as serum and cell culture media. Exponential phase cells were much more susceptible to the lethal effects of the parabens than were the stationary phase cells.

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Patients who do not exhibit early motor recovery post thrombolysis may benefit from more aggressive treatment. arthroplasty for fractures of the proximal humerus that arises in large part from patient and surgeon factors. These findings suggest that sites of ADP-ribosylation in the unassembled tubulin molecule are crucial for tubulin assembly, and that covalently attached ADP-ribose moieties interfere with tubulin interaction by steric hindrance or conformational change.

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The Epworth sleepiness scale gives a subjective estimate of the level of sleepiness by asking the patient to estimate the probability of falling asleep during each of eight activities of daily living. Treatment of phalangeal fractures: recommendations of the Hand Surgery Group of the German Trauma Society Antenatal consent in the SUPPORT trial: challenges, costs, and representative enrollment.

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Off-label therapy from the perspective of the medical insurance service officinalis extract-induced cell growth inhibition appears to be linked to the activation of p38 MAP kinase through p21WAF1 expression. It is concluded that VCFS is associated with a specific psychopathological syndrome. The ripple artifact is an important limitation of gradient selection based MSI techniques, and can be understood using the presented simulations. From August 1998 to June 2016, 682 patients (301 female, 381 male) underwent 1713 gastrostomy tube changes in the medical setting, with an average age of 7.59years and an average site age of 3.43years.

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The resulting surface tension changes due to a step-type surface area disturbance, as a function of time, were measured through a capillary wave probe. Steroidogenesis in ovarian tissue of a viviparous teleost, the guppy Poecilia reticulata.

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To perform baseline T2 mapping of the hips of healthy volunteers, focusing on topographic variation, because no detailed study has involved hips. Using ChIA-PET and Hi-C data derived from human B-lymphocytes, we demonstrate the effectiveness of 3D-GNOME in building 3D genome models at multiple levels, including the entire genome, individual chromosomes, and specific segments at megabase (Mb) and kilobase (kb) resolutions of single average and ensemble structures. These studies have explored the role of cognitive biases, such as confirmation and availability bias, in diagnostic mistakes.

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Each BD stenting allowed her to eat chopped food, but the anastomotic stricture recurred 4-7 months after the procedure. The over-the-scope clip (OTSC) is a device used for endoscopic closure of perforations, leaks and fistulas, and for endoscopic hemostasis. Outcomes After Implementation of an Alcohol Withdrawal Protocol at a Single Institution. This result suggests that the maintenance of nucleotide variability within target genes provides an opportunity for the evolution of SU-R phenotypes by herbicide-driven selection for mutations conferring resistance. Recurrence of glomerulonephritis (GN) is one of the major risk factors of long-surviving renal graft dysfunction.

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The hyperplasia is characterized by a loss of the ordered stacking of cornified cells which become shorter and thicker than normal. By contrast, phages displaying mutant barnases at this site were resistant to proteolysis, but were cleaved and their infectivity was destroyed as the temperature was raised. We investigated four adverse fetal outcomes: stillbirth, miscarriage, preterm birth, and low birthweight. Literature was searched using PubMed, Embase and ISI/Web of Science.

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However, if we consider improvement to phosphate removal by dialysis procedures, full dialyzer clearance is effective in only the initial phase of the dialysis treatment. Poster 487 Chronic Inflammatory Demyelinating Polyneuropathy or Something Else?: A Case Report. trachomatis replication is largely dependent on the induction of a family of IFN-gamma-inducible GTPases called immunity-related GTPases or IRGs.

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Haplogroup ages were estimated in the networks of high-frequency haplogroups (B, F, M7, R), and they were found to originate about 50,000 years ago. Modification of directed-loop algorithm for continuous space simulation of bosonic systems.

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Social physique anxiety related to a negative body image and risk for developing an eating disorder as assessed by Body Dissatisfaction and Drive for Thinness in young females. Yeast mitochondria contain a minimalist threonyl-tRNA synthetase (ThrRS) composed only of the catalytic core and tRNA binding domain but lacking the entire editing domain.

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Upon activation, this kinase cascade modulates gene expression vergon 5 mg through the phosphorylation and inhibition of transcription co-activators that are involved in cell proliferation, differentiation, growth and apoptosis. The posterior single implant crown: simplicity and productivity.

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Synaptosomal uptake of noradrenaline (IC50 239 microM) and dopamine (IC50 322 microM) was also inhibited. Psychometric Properties of a Generic, Patient-Centred Palliative Care Outcome Measure of Symptom Burden for People with Progressive Long Term Neurological Conditions. The major focus that distinguishes this review from the current literature is the thorough discussion on the key features of native valve microenvironments and various up-and-coming approaches to engineer synthetic elastomers to recreate these features such as anisotropic tri-layered architecture, mechanical anisotropy, biodegradability amorion gameplay store and biocompatibility. Fundamental aspects of electric double layer force-distance measurements at liquid-solid interfaces using atomic force microscopy.

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Importance of a sound hydrologic foundation for assessing the future of the High Plains Aquifer in Kansas. However, the imported malaria cases are increasing in recent years, and the surveillance and management of them should be paid more attention to. Our population-based nationwide study used 2000-2013 the National Health Insurance Research Database of Taiwan. Value of MR imaging in differentiating benign from malignant soft-tissue masses: study of 95 lesions. omeprazole tablets can they be crushed The patients underwent application of 2-octyl-cyanoacrylate onto the perforated or leaking site, and a hydrogel contact lens was applied as a bandage.

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Insights into the putative catechin and epicatechin transport across blood-brain barrier. The rich information associated with hyperspectral images allow for the examination between cefpodoxime dosage for humans cancerous and healthy tissue. We detail the active control strategy, with an emphasis on the electronic circuitry, based on a simple phase-locked-loop integrated circuit. Asthma prevalence has dramatically increased over the last decade in Westernized societies, thereby suggesting a key function of environmental factors in disease promotion and development.

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A technology to reliably assess the spatial distribution of intermediate host snail habitats on farms would be a major step forward to this respect. Spinal reflex conditioning changes reflex size, induces spinal cord plasticity, and modifies locomotion. Association of mitochondrial haplogroup D and risk of esophageal cancer in Taihang Mountain and Chaoshan areas in China. None of the studied autosomal markers were found to be associated with HPRL. A recently proposed logistic regression-based method for meta-analysis of case-control bactrim ds safe while breastfeeding genetic association studies was used to analyse pooled data.

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Seven previously untreated patients were entered into treatment. Do Infant Temperament Characteristics Predict Core Academic Abilities in Preschool-Aged Children? Methylsiloxanes mikrowellen baclofen overdose Release from One Landfill through Yearly Cycle and Their Removal Mechanisms (Especially Hydroxylation) In Leachates.

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The presence of atherosclerosis is associated lamictal coupons with higher ADMA levels in patients with normal renal function as well as in dialysis patients, but this phenomenon may be unrelated to renal handling of ADMA. There is good evidence that angiogenesis plays an important role in a wide range of cutaneous maladies, and angiogenesis-targeting therapies are playing an increasing role in the management of dermatologic disease. Please see related commentary: Astrocytes present at neural synapses are thought to contribute to synaptogenesis through cholesterol release and normally exhibit increased glial fibrillary acid protein (GFAP) reactivity and apolipoprotein E (apoE) expression in neurodegenerative disease states. However, to date, this relationship has not been examined in any indigenous population.

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In immunocytochemistry was used to analyze the expression of CMTM1-v17 in prostate carcinoma originated cell lines. To address lansoprazole dose for pediatrics this need, we conducted a systematic review to examine the impact of EMRs in the physician office, factors that influenced their success, and the lessons learned. However, lymphatic vessels complexity and its proximity with the venous system suggest the need for further researches, especially in the comprehension of pulmonary symptoms. In this study, we examined hip and knee joint kinetics during stair climbing in 35 young healthy subjects using a subject-specific knee model to estimate bone-on-bone tibiofemoral and patello-femoral joint contact forces. They were designated as R1, R2, R3, R4, R5, R6, and R7, whose molecular weights were estimated to be 1.15x10-6, 0.75x10-6, 0.55x10-6, 0.40x10-6, 0.30x10-6, 0.25x10-6, 0.20x10-6 daltons, respectively.