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Efamat (Efavirenz)

Efamat is marketed by Bristol-Myers Squibb under the trade name Efamat in the United States, United Kingdom, Ireland, France, Germany, Italy, and Spain. The trade name Stocrin is used by Merck Sharp & Dohme, who market the drug in other European countries, Australia, Brazil, Latin America, South Africa and other regions. Numerous generic versions of Efamat, either alone or co-formulated with other drugs, are available. Efamat is also available in a triple-drug combination tablet called Atripla. This tablet is the first once-daily tablet containing a complete HIV treatment regimen. It contains 600mg Efamat, 200mg emtricitabine (FTC), and 300mg tenofovir. It was approved in the United States in July 2006 and in the European Union and Canada in late 2007.

Other names for this medication:
Efavirenz, Adiva, Aviranz, Efamat, Efavir, Efcure, Efferven, Estiva, Stocrin, Sustiva,

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The approach is based on isometric log-ratio transformation and has been previously proposed for the construction of regression models using compositional explanatory variables. Here, we have used second harmonic generation (SHG) to image human tissues on the hundreds of micron scale, and developed a numerical model to quantitatively interpret the images in terms of the underlying collagen structure on the tens to hundreds of nanometer scale. Effects of shRNA-Mediated SOX9 Inhibition on Cell Proliferation and Apoptosis in Human HCC Cell Line Hep3B Mediated by Ultrasound-Targeted Microbubble Destruction (UTMD).

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Neoplastic Paneth cells in the experimental murine carcinoma of the small intestine. Because of possible selection biases, these results must be interpreted with caution. The apelinergic system is a mammalian peptide hormone network with key physiological roles.

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Proteome-wide analysis reveals an age-associated cellular phenotype of in situ aged human fibroblasts. After the induction of sedation, we treated patients with a continuous infusion of normal saline at a rate of 0.3 ml/kg/h in group I and the same volume of propofol in group II.

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Restrictive mitral annuloplasty with or without surgical ventricular reconstruction in ischaemic cardiomyopathy: impacts on neurohormonal activation, reverse left ventricular remodelling and survival. We detected a significantly higher expression of C19MC miRNAs in non-seminomas than in seminomas and in clinical stages 2 and 3 than in stage 1 in both tissue and serum samples.

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Angiogenesis has been investigated in different kinds of anemia. The self-assembled polymeric nanomedicine could act as an efficient therapy method for HCC treatment. Sixty patients with epithelial endometrial cancer and pelvic node metastasis were managed surgically between 1984 and 1993 at the Mayo Clinic.

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S-14 infusion results in a decrease of pancreatic juice leaks from the pancreatic remnant. If additional explanation or details for molecular techniques are required, the reader is advised to consult Current Protocols in Molecular Biology (CPMB). Histone deacetylase inhibitor suberoylanilide hydroxamic acid exhibits anti-inflammatory activities through induction of mitochondrial damage and apoptosis in activated lymphocytes.

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Using Custom Fiber Bragg Grating-Based Sensors to Monitor Artificial Landslides. The resultant massive ascites caused thoracic and cardiac compression and subsequent hydrops fetalis. Scanning electron microscopy showed that HMC-1 5C6 cells adhere to HCAEC in cocultures. Accurate quantification of water-macromolecule exchange induced frequency shift: effects of reference substance.

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This article reviews the main new technologies that produced this revolution. Out of which, six strains with higher value of percent inhibition of fungal mycelium in dual plate assay were selected. The predetermined high-risk children in terms of the development of anxiety play an important role in reducing the negative consequences.

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Based on the recent pathognomic accomplishment in the mechanisms of toxic actions, the favorable degree of protection was achieved by several drugs in acute poisoning of rats with sulfur and nitrogen mustards. Similarly, flow- assisted HF etching of a custom microstructured fiber containing nine microchannels produces nine individual microlenses simultaneously at the fiber facet, where each microaxicon lens shows a similar focusing pattern. Embelin treatment also caused a significant increase in the microsomal glucose-6-phosphatase and the cytosolic enzyme, lactate dehydrogenase. However, prospective studies are warranted to establish factors that are specifically associated with pediatric PRES.

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Both zimelidine and clorgyline decreased levels of PPT mRNA in medullary raphe neurons and SP-LI in the ventral spinal cord. Intervention effects decayed somewhat for BMI and completely for AEC over 6 months.

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Arterial blood pressure (BP) and renal nerve activity (RN) were recorded. Modification of human cytomegalovirus tropism through propagation in vitro is associated with changes in the viral genome. This study analyses the association between ABO blood group phenotypes in relation to placental malaria pathology and birth outcomes in southern Malawi, an area with perennial malaria transmission. The sub-G1 fraction, which can be considered as the apoptotic cell population, appeared more rapidly with CPT than with NB-506 but in both cases, the cell cycle perturbation was accompanied by a marked decrease in the mitochondrial transmembrane potential and the intracellular pH. No rat developed vocal cord dysfunction after cryotherapy and no significant changes in serum calcium level before and after cryotherapy were observed.

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The level of expression of the 3.0 and 4.0 kb transcripts of this gene decreased in concert during the organelle division phase of a synchronized culture, indicating a cell-cycle-dependent manner of ftsH2 transcription, while northern hybridization did not detect ftsHcp transcripts. Effect of halofenate and clofibrate on lipid synthesis in rat adipocytes. A number of symptoms that are presently not included in the ICHD-2 classification may help in differe-ntiating the migraine from the TTH. Monthly mortality data were compiled from 19 countries, amounting to over 54 million deaths. Spot variation in 2D pattern for the natural IgM could be expressed as a binomial signature, which opens up the way to correlate a particular pattern with resistance or susceptibility.

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Quercetin inhibits proliferation and drug resistance in KB/VCR oral cancer cells and enhances its sensitivity to vincristine. Malignant hyperthermia is a rare syndrome that occurs in genetically susceptible individuals who are exposed to frequently used inhalation anesthetics. In ileum, five genes were down-regulated and six genes were unchanged in SBS vs sham animals. Fused aromatic 1H and 2H-indazoles are well recognized for anti-hypertensive and anti-cancer properties. The purpose of this study was to determine the maximum tolerated dose and toxicities of suramin when administered using a fixed dosing scheme on a once- or twice-monthly schedule.

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Relative staining area for corticotropin-releasing hormone or neurophysin II, a vasopressin carrier protein, was increased in the external zone of the median eminence in vehicle control, but was equivalent to that of intact control in the dexamethasone-injected group. Influence of Helicobacter pylori on gastroesophageal reflux disease In selected patients temporal lobectomies and hemispherectomies may totally eliminate seizures while corpus callosotomies frequently reduce number and severity of generalized seizures. These results suggest that IL-6 may attenuate E(2) production partially by inhibiting the expression of aromatase mRNA as an intraovarian regulator for suppressing GC maturation.

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Females who reported date fighting were more likely than were nonfighters to have attempted suicide, to engage in sexual and human immunodeficiency virus risk behaviors (use of injectable drugs), to have been pregnant, experienced forced sex, and to have ridden in a car with a drinking driver. Midterm durability of abdominal aortic aneurysm endograft repair: a word of caution.

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The number of hemidesmosomes/microm of BM was decreased in all insulin treated ponies. The author describes a model for the initiation and pathogenesis of hyperacute rejection. The EIA analyses showed that the concentration of tachykinin in the tissue on both sides increased in a time-dependent manner.

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Through a combination of recorded conversations, published speeches, and correspondence, insights are gained into some perspectives of William Rush Dunton, Jr., MD (1868-1966), one of the founders of the occupational therapy movement. The infusion of hypertonic saline is now used commonly by physicians. infusion of lipid, glucose disposal during a hyperinsulinemic-euglycemic clamp is reduced. The toxic Cr(VI) in industrial wastewaters can be removed by a reduction from Cr(VI) to Cr(III) and a followed precipitation treatment.

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Injection sclerotherapy, now standard treatment for bleeding esophageal varices, is capable of controlling acute variceal bleeding and is equally effective or better than surgical procedures such as portosystemic shunts and esophageal transection. Histologic findings in specimens obtained by percutaneous directional coronary atherectomy.

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Importance of Vibronic Effects in the UV-Vis Spectrum of the 7,7,8,8-Tetracyanoquinodimethane Anion. This made it possible to explore the issue of whether the initial rise represents a true marker of focus in the traditional sense, or whether the association is less direct.

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Together, our data strongly suggest that syntaxin 5-mediated retrograde transport to the Golgi apparatus is a broadly conserved feature of AAV trafficking that appears to be independent of the identity of the receptors used for viral attachment. Results revealed that participants with fewer FMRP-positive lymphocytes exhibited lower performances on tests biasing information processing toward the magnocellular pathway and dorsal visual stream (contrast sensitivity at low spatial/high temporal frequency and motion coherence).

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Results showed that marginal contraction gaps at the dentin-restoration interface among the four sites in both treated and untreated cavities are not statistically different in size. Straightforward reports of unusual drug experiences are included in this section. Sentinel lymph node (SLN) biopsy may be the evidence for individual treatment of cN0 neck. Observations of mitosis in these unusual cells support the involvement of the preprophase band/phragmosome in properly positioning the preprophase nucleus, influencing spindle orientation such that the cytokinetic phragmoplast initially grows in an appropriate direction, and delineating a region in the cell cortex that attracts microtubules and directs later stages of phragmoplast growth.

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Pathological features are the main determinant of follow-up therapy but have limited ability to identify patients at risk of recurrence. Public awareness of aesthetic and other forest values associated with sustainable forest management: a cross-cultural comparison among the public in four countries. The electrostatic interactions are taken into account through an effective two-body potential, obtained within the nonlinear Poisson-Boltzmann formalism, which has the form of anisotropic screened Coulomb potential. In light of these two possible outcomes, PRR needs to be tightly controlled in order to prevent the accumulation of mutations leading ultimately to genome instability. Dynamic control of arterial blood pressure by the sympathetic baroreflex.

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Biofilm dissolution and cleaning ability of different irrigant solutions on intraorally infected dentin. This study aimed at evaluating the impact of socio-demographic determinants on self-assessed health status and frequency of health complaints in workers employed in a large institution as well as the perception of the influence of working conditions on their health and the occurrence of selected diseases and health complaints. Furthermore, one example is provided where experimental overexpression of a DNA construct can be visually verified after comparison with control samples.

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In our manual evaluation, we achieved an F1 score of .71 and .73 for detecting topic drift and counteracting efforts to stay on topic, respectively. Duty cycle (DC) represents an understudied element of CPR quality. The interviews were considered helpful: sharing problems was therapeutic and being able to contribute to research was empowering. The novel finding is that tumor microenvironment may play a significant role in determining the prognostic impact of stem/progenitor cells in human breast tumors. Metabolic assessment were analyzed in urinary excretion of oxalate and citrate.

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In this randomized, open-label, two-period, two-treatment crossover, single-dose study, healthy subjects received daytime and nighttime oral dosing of fesoterodine 8-mg sustained-release tablets, separated by a minimum 60-h washout period. Cytokine receptor repertoire and cytokine responsiveness of Ho(dull)/Rh(dull) stem cells with differing potentials for G1/S phase progression. Inhibition of ADP-triggered blood platelet aggregation by diadenosine polyphosphate analogues. Prognostic model for predicting hearing recovery in idiopathic sudden sensorineural hearing loss.

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Capillary electrophoresis comprises a group of techniques used to separate chemical mixtures. Due to the heterogeneous nature of the client proteins this transport system displays several unique features. The tobacco-induced neurotoxicity of adolescent cognitive development (TINACD) theory postulates that alterations in executive functioning, particularly evident under stressful or emotionally intense states, lead to higher levels of dependence. Recent data have shown that an elevated plasma level of the amino acid homocysteine (Hcy) is a common, independent, easily modifiable and possibly causal risk factor for cardiovascular disease (CVD) which may be of equal importance to hypercholesterolemia, hypertension and smoking. GRIM REAPER peptide binds to receptor kinase PRK5 to trigger cell death in Arabidopsis.

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A coherent clinical evidence base is emerging demonstrating remission of albuminuria following bariatric surgery in patients with obesity and diabetes. Eosinophil and goblet cell numbers were counted, epithelial thickness was measured, and the symptoms were characterized and graded. Action Research Arm Test (ARAT) and acceleration metrics quantified from accelerometer recordings.

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Submillisievert Radiation Dose Coronary CT Angiography: Clinical Impact of the Knowledge-Based Iterative Model Reconstruction. However, the link between thyroid homeostasis and microbiota composition is not yet completely ascertained. There was little change in the proportion of Gleason score 7, 8, 9 and 10 tumors between the 2 periods.

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Defective circulating dendritic cells (DCs) have been described in systemic lupus erythematosus (SLE) and correlated with high levels of interferon-alpha (IFNalpha). The incidence of carcinoma in patients undergoing operation for nodular goiter increased from 8.7 per cent in the early years to 20.4 per cent in the past four years. Microbiologic investigation of an epizootic of mastitis caused by Serratia marcescens in a dairy herd. Triterpene esters from Uncaria rhynchophylla drive potent IL-12-dependent Th1 polarization. The clone containing the OASS gene was selected by using tetracycline-ammonium bismuth citrate medium.

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Marked reduction in density of protein expression was observed with the extract from the mutant (resistant) clone compared with the parent (sensitive) clone. Thirty-four patients with cystic intracerebral mass lesions (28 tumors, six abscesses) were examined at 1H MR spectroscopy in vivo. In addition, intracellular CB(1) receptors and mitochondrial mechanisms contributed to endocannabinoid-dependent depolarization-induced suppression of inhibition in the hippocampus. In this study, 88 patients 6-17 years of age, with ADHD and ASD, were treated with 1.2 mg/kg/day atomoxetine for 20 weeks as follow-up of an 8 week double-blind placebo-controlled period. To evaluate the diagnostic accuracy of primary and secondary magnetic resonance (MR) imaging findings of anterior cruciate ligament (ACL) tears in young patients with immature skeletal systems.

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Therefore, the volume and distribution of bone cement should be considered as 2 distinct variables to evaluate the effectiveness of PKP. No drug is effective on all phases or effector cells of the immune response and it is postulated that in a near future combined therapies will be attempted with antibiotics or anti-cancer agents.

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Efficacy of ISA247 in plaque psoriasis: a randomised, multicentre, double-blind, placebo-controlled phase III study. Its high case fatality warrants adequate and compliant prophylactic therapy in severely immune depressed patients as well as early initiation of antiretroviral therapy in HIV-infected patients.

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Localization and functional expression of alternatively spliced forms of the GABA(A) receptor gamma(2) subunit. Subthreshold (invisible) diode laser modified grid photocoagulation substantially reduces the post-treatment atrophic scarring.

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These compounds are composed of a hydrophilic head group and an apolar isoprenoid side chain, giving the molecules a lipid-soluble character. An immunohistochemical and ultrastructural study on age-related astrocytic gliosis in the central nervous system of dogs. These findings suggest a mechanistic explanation for the diverse clinical observations associated with dexrazoxane. Clinical management of these lesions is based on whether or not the fragments are attached. Universal infant immunization and occult hepatitis B virus infection in children and adolescents: a population-based study.

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Moreover, LRIP in ULL indicated a better effect in reducing infarct size than LRIP in BUL and BLL. We also describe for the first time sialyltransferase activity in these cells and report that the levels of this activity correlated with the decrease in PSA-NCAM expression during the differentiation of astrocytes. Cutaneous B-cell lymphomas: 2016 update on diagnosis, risk-stratification, and management.

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The diagnosis was mainly based on findings of magnetic cutaclin gel dosis dalsy resonance imaging. For purely hepatic problems 18F-fluorodeoxyglucose (FDG)-PET/CT using diagnostic CT data has a higher precision than CT alone but is inferior to MRI. Hippocampal EEG spectral power uniformly decreased during behavioral activation.

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Four examiners (two consultant ophthalmologists and two other clinicians) were shown 142 retinal haemorrhages on 31 RetCam photographs. The soluble platelet secreted ligand CD40 (sCD40L) has a role in atherosclerosis progression. Concentrations of lactoferrin and iron in human milk at different stages of lactation. tac dung verospiron 25 mg of zoloft Immunologic aspects of isocyanate asthma: IL-1 beta, IL-3, IL-4, sIL2R, and sICAM-1. Chloride of Ammonium in the Treatment of Hepatic Disease in India.

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Data routinely recorded by the physical therapist at each home visit related to ambulatory progression and physical status was used in analysis. Adults with low incomes had the highest rates of steep out-of-pocket costs. Shigella-associated diarrhea in children in South Jakarta, Indonesia. In the presence of ACh, both blockers retarded the reaction of extracellularly applied MTSEA with cysteine substituted for residues from alphaVal255, one third of carbatrol interactions the distance in from the extracellular end of M2, to alphaGlu241, flanking the intracellular end of M2, but not with cysteine substituted for alphaLeu258 or alphaGlu262, at the extracellular end of M2.

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Seventy-seven percent of survivors failed to identify pain in the jaw, neck, or back as a heart attack symptom. Distant metronidazole cream yeast infection metastasis remains an important first relapse and may warrant more aggressive systemic treatment.

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Overall, these findings support the hypothesis that introduced earthworms facilitate particular plant species adapted to the abiotic conditions of earthworm-invaded forests. Coexpression with the pro alpha1(I) chains, which were produced at half the level of the pro alpha1(III) chains, gave a half-life of 6.5 h. One lek pharmaceuticals amoxicillin clavulanate augmentin hundred and fifty cases of invasive breast carcinoma were evaluated for type, grade and stage and studied immunohistochemically for estrogen receptor, progesterone receptor, Her2/neu and androgen expression. Spectral molecular imaging is a new X-ray-based imaging technology providing highly specific 3D imaging at high spatial resolution that has the potential to measure disease activity and response to treatment noninvasively.

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Reduced primazole medication identification level of anxiety in adult Lewis rats after chronic ethanol consumption. A 61-year-old male taxi driver suddenly became unable to operate a taximeter, and a 66-year-old female janitor suddenly became unable to use a fax machine. The effects of different intensities of exercise and active vitamin D on mouse bone mass and bone strength. Between September 1994 and September 1996, 292 patients with 316 ovarian tumors were treated laparoscopically in the Department of Obstetrics-Gynaecology, University of Ulm. An oesophagogram was helpful for the diagnosis in those circumstances.

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After local anesthesia, the right eyebrow of 20 patients was treated with Ultrapulse CO2 laser with the parameters of 4 J/cm(2) and 3.2 J/cm(2) for the first and the second passes. Furthermore, participants responded faster to targets behind distractors (orienting redundancy). purinol 300 mg tabletten fur Knowledge of the variations of liver supplying arteries helps the interventionalist to embolize necessary vessels prior to RE. Maternity care practices encompassed in the 10 Steps to Successful Breastfeeding are positively associated with improved breastfeeding outcomes.

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Boo et Brawley, we azibiot 500 mg alkohole tested the effects of the Rac1-specific inhibitory compound, NSC23766, on actin dependent processes and on actin arrays. The data might contribute to the understanding of the mechanisms by which sensory input deprivation-induced plasticity modifies cerebral electrophysiological responses in the developing brain.

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RTI processes potentially integrate general and special education and suggest new directions for research and public policy related to LDs, but the scaling issues in schools are significant and more research is needed on the use of RTI data for identification. The buy finasteride 5mg uk electro-anatomical mapping system, CARTO system, can records entire circuit of arrhythmia and point the critical area, but it will expend more time for mapping and can not indicate for unstable arrhythmias. Prairie pothole lakes (PPLs) are located within the extensively farmed Great Plains region of North America, and many are negatively impacted by nonpoint source pesticide pollution. We measured scaffold area every 0.25 mm and acquired a total of 115 paired cross-sections.

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To maximize the quality of the information obtained, antibody conjugate panels need to be developed assert 100 mg gabapentin with care, including requisite controls at every step. This procedure allows rapid and easy transfer of a wide variety of mutant allelic DNA to the bacterial chromosome, and should be adaptable to various bacteria besides Xanthomonas spp. As part of a new MRI-linac program, an MRI scanner was integrated with a linear accelerator to enable investigations of a coupled inline MRI-linac system.

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The inhalation of Lavandula angustifolia (lavender) essential oil has anxiolytic-like effects in animal models and humans, but its mechanism of action is still not fully understood. In humira pregnancy category bactrim this paper gyro and eye-in-hand camera data are adopted as an alternative choice for solving this problem. To evaluate the knowledge of CVD risk factors among soldiers of the Polish Army and try to identify a demographic factors influenced on them. Removal of selected pharmaceuticals from domestic wastewater in an activated sludge system followed by a horizontal subsurface flow bed - analysis of their respective contributions.