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Epivir (Lamivudine)
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Lamivudine

Epivir is an antiviral drug that reduces the amount of HIV in the body. Anti-HIV drugs such as Epivir slow down or prevent damage to the immune system, and reduce the risk of developing AIDS-related illnesses. Epivir is also active against hepatitis B virus (HBV). Epivir is one of the nucleoside reverse transcriptase inhibitors (NRTIs). These drugs disrupt an HIV protein or enzyme called reverse transcriptase, which is involved in making new viruses. For more information about how NRTIs work, see Nucleoside RT inhibitors. In 1996, Epivir was licensed in Europe as a treatment for HIV when used in combination with other anti-HIV drugs. It was discovered by BioChem Pharma and is manufactured by ViiV Healthcare under the trade name Epivir. Numerous generic versions of Epivir are available. The latest news and research on HIV treatment. Epivir is available as part of several co-formulations.

Other names for this medication:
Lamivudine, Epivir, Heptovir, Lamivudina, Lamzid, Zeffix,

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Design and synthesis of N-alkyl oxindolylidene acetic acids as a new class of potent Cdc25A inhibitors. Complete resection is the key to prevent recurrence and the prognosis is excellent following surgery. We observed morphological differentiation as evidenced by the appearance of differentiating lentoid structures associated with fibroblasts. Results revealed domains labeled Stress, Relationships, Coping, Expectations, Perfectionism, and Academic/Professional Goals.

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Localizing Perturbations of the Racemic Equilibria Involving Dipicolinate-Derived Lanthanide(III) Complexes. A gene-dosage mechanism in CMT1A and HNPP has been postulated previously. Computed tomographic (CT) based navigation is a technique to improve the accuracy of pedicle screw placement. Our results demonstrate a large pharmacokinetic advantage of intrathecal gemcitabine and support a planned Phase I clinical trial of this dosing strategy. Results suggested that the communitas domain was evinced in the various seduction strategies.

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Conversion equations for milk yield were computed by least squares, Goddard, and Wilmink methods. The aim of this retrospective questionnaire study was to directly assess patient satisfaction with their current bone-anchored hearing aid in comparison with their previous conventional air and/or bone-conduction hearing aids. The test fluid was seeded with 10 microm polystyrene spheres, and the motion of these particles was used to determine the instantaneous flow velocity distribution in the illumination plane.

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The focus is on their suitability as magnetic multifunctional theranostic agents analyzing their T2 contrast enhancing capability for magnetic resonance imaging (MRI) and their magnetic hyperthermia performance. Hypoxic incubation at day 10 as well as in vitro incubation of isolated RBC with cAMP-elevating agonists strongly induces erythroid caII expression. A second contact between InlB and the Met Sema domain locks the otherwise flexible receptor in a rigid, signaling competent conformation.

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Data of ethnic background and religion were available for 557 of 643 deceased patients. Findings from the current study may be used to inform the development of user-centered lifestyle interventions. Despite numerous publications on unplanned extubation, few studies assess preventive strategies for adverse events, and few clinical trials have assessed unplanned extubations.

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B52, an essential SR protein of Drosophila melanogaster, stimulates pre-mRNA splicing in splicing-deficient mammalian S100 extracts. The results show that the size of the soft tissue punch plays an important role in achieving optimal healing. For a PTSD population with chronic and early-life trauma, a phase-based skills-to-exposure treatment was associated with greater benefits and fewer adverse effects than treatments that excluded either skills training or exposure. This study compares the 1-day prevalence of the AEs obtained in the IBEAS Study with the incidence obtained through the retrospective cohort study.

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Video-assisted pericardial fenestration for effusions after cardiac surgery. The emphasis is laid on newly uncovered catalytic systems and mechanisms of carbohydrate transformations. The SNPs detected at codons 100 and 226 induced amino acid substitutions.

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It was the objective of this study to see if any specific therapeutic goals such as reversal of the neurological deterioration and sensorimotor deficits associated with the syndrome could be achieved by performing Titanium mesh cranioplasty to reconstruct the missing part of the cranial shield in these patients. We examined FGFBP1 and WISP-2 expression in 46 SC/ASC and 80 AC samples using immunohistochemistry and analyzed their correlations with clinicopathological characteristics.

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We also devise a strategy to automatically generate the trimap required for matte estimation. In the neighborhood of a Landau multicritical point, solutions of the statistical problem can be written as a Landau-de Gennes expansion for the free energy. Histamine H4 receptor ligands and their potential therapeutic applications: an update.

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We present two cases of a hyoid bone fracture identified through careful clinical examination with a Valsalva manoeuvre during nasendoscopy. Protein folding pathways and kinetics: molecular dynamics simulations of beta-strand motifs. Racial groups within the older population present distinctive profiles of religious participation and spirituality. Genome-wide analysis reveals SR protein cooperation and competition in regulated splicing. Gonorrhea is a major global health concern, caused by the bacterium Neisseria gonorrhoeae.

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In this study, we examined whether adolescent attempts were associated with impairments related to suicidality, psychopathology, and psychosocial functioning in adulthood (objective 1) and whether these impairments were better accounted for by concurrent adolescent confounders (objective 2). Raf-mediated regulation of this site could be a crucial mechanism involved in the functional switching of eEF1A between its role in protein biosynthesis and its participation in other cellular processes. crassicaulis showed a far genetic relationship with the other five species.

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In addition, 2a reduced the sizes of a number of human tumour xenografts including colon, prostatic and melanotic cancers passaged in athymic mice. The outcome of children whose epilepsy starts between the ages of 28 days and 2 years is determined by the underlying brain disease, and the outcome is good in cryptogenic cases. Hypothalamic AMP-activated protein kinase (AMPK) has been suggested to act as a key sensing mechanism, responding to hormones and nutrients in the regulation of energy homeostasis. Genetic linkage map of the house musk shrew, Suncus murinus, constructed with PCR-based and RFLP markers. Growth hormone response during oral glucose tolerance test: the impact of assay method on the estimation of reference values in patients with acromegaly and in healthy controls, and the role of gender, age, and body mass index.

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Passive administration of specific protective monoclonal antibodies could also prove to be beneficial in drug resistance cases, to reduce the dosage and associated toxic symptoms of anti-fungal drugs. Biologically Informed Individual-Based Network Model for Rift Valley Fever in the US and Evaluation of Mitigation Strategies. To investigate pain-related expression of NaV1.7 in dorsal root ganglia (DRG) innervating intervertebral discs. Effects of environmental conditions on the nitrifying population dynamics in a pilot wastewater treatment plant.

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Establishment and Clinical Application of an Electronic Database for Breast Cancer in China. Transplantation of bone marrow-derived mesenchymal stem cells facilitates epithelial repair and relieves the impairment of gastrointestinal function in a rat model of enteritis.

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Animals were euthanized and the brains were used for measurements of brain edema and PAR-1 expression. HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 (HACE1) regulates a wide variety of cellular processes. Clinical experience of early percutaneous drainage of amebic hepatic abscess

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Early and Late Results of the Nuss Procedure in Surgical Treatment of Pectus Excavatum in Different Age Groups. Comparison of static end-expiratory and effective lung volumes for gas exchange in healthy and surfactant-depleted lungs. Ethical Issues--the challenge to keep up with a changing environment. SD-OCT quantitative measures of reflectivity and/or thickness of specific groups of retinal layers and/or ROIs correlate with improvement in BCVA.

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Currently, the most widely used mechanism for monitoring HLB is exploration, which is an expensive, labor-intensive, and time-consuming process. The accumulation of insoluble proteins within neurons and glia cells is a pathological hallmark of several neurodegenerative diseases. This, we believe, is the first evidence of active HIV infection following administration of 60 degrees C, 30 h heat-treated factor VIII.

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Hearing impairment is a common and frequently permanent sequel of Streptococcus suis meningitis in humans. Sheath closure after tendon grafting was accomplished by trapdoor of the original sheath, vein patch, and vein conduit. Increasing understanding of the optimal approach to supplementation will depend upon results from interventional studies that also carefully evaluate and analyze well-established factors for these two conditions.

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Monitoring of solid phase peptide synthesis by an automated spectrophotometric picrate method. Two of 104 mummy bone marrow specimens yielded a band of human beta-globin gene DNA 110 base pairs in length, and one of these two produced bands of HTLV-I-pX (open reading frame encoding p40x, p27x) and HTLV-I-LTR (long terminal repeat) gene DNA 159 base pairs and 157 base pairs in length, respectively. SAR was calculated as the ratio of the abnormal to total area on the GCC significance map. Significant differences in the electrophysiological parameters were observed between the two groups at higher doses of penicillin (20 to 30 IU). The planar image-based method developed in this study resulted in similar absorbed doses to the bone marrow as reported in earlier studies with blood-based bone marrow dosimetry.

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Overexpression of cyclin D2 is associated with increased in vivo invasiveness of human squamous carcinoma cells. Pentose phosphate pathway (PPP) plays a pivotal role in meeting the anabolic demands for cancer cells. RESULTS indicate very good intrarater Intraclass Correlation Coefficient (ICC) for the MTAi, good intrarater ICC for the 2D-MTA, yrMTA and yrRMTA and also good interrater ICC for the MTAi, 2D-MTA, yrMTA and yrRMTA. During learning trials, epileptic rats made significantly more errors than controls.

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A Novel Tetraenoic Fatty Acid Isolated from Amaranthus spinosus Inhibits Proliferation and Induces Apoptosis of Human Liver Cancer Cells. This cohort study evaluates the relationship between TS and depression in Taiwan.

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The ability of cells to transition between proliferating and nonproliferating states is essential for the proper formation of tissues. Early recognition and treatment of pediatric stroke is however critical in optimizing long-term functional outcomes, reducing morbidity and mortality, and preventing recurrent stroke. aerophoba from a scale of hundred of meters to thousand kilometers. An anatomic study on the junctura tendinum in the 4th intermetacarpal space and its clinical implication. To investigate differences in ad libitum food intake, feelings of hunger and satiety and the systemic levels of cholecystokinin (CCK), glucagon-like peptide-1 (GLP-1), peptide YY (PYY), glucose and insulin after intraduodenal, intrajejunal and intraileal protein infusion.

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We decompose daily data from U.S., British, Brazilian and Hong Kong stock markets indices in order to calculate the scale correlation between their illiquidities. A survey of smokers age at least 18 years visiting an American urban emergency department from April to July, 2013. These structures display a fold that is common for condensing enzymes. Allergic fungal airway disease: pathophysiologic and diagnostic considerations.

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There was a post-imbibition initial surge of activity with short- and mid-chain-length substrates. Absolute structural elucidation of natural products--a focus on quantum-mechanical calculations of solid-state CD spectra. To examine the effect of measurement error in dietary data on the relationship between diet and body mass index (BMI).

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With a focus on human pathogen Mycobacterium tuberculosis H37Rv, we show that such scrupulous use of details at the molecular level can predict physicochemically viable protein-protein interactions across host and pathogen. The secondary outcome was the presence or absence of a periprocedural red blood cell transfusion occurring within 72 hours of needle placement. Our study therefore aimed to record traditional knowledge, use, nomenclature and classification of wild mushrooms in four Mixtec communities and to analyze how these aspects vary according to environmental and cultural conditions among the studied communities.

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We demonstrate the potential of the miniature device to obtain controlled evacuation without the use of highly pressurized motive fluids. This report describes two episodes of significant uvular and oropharyngeal ulceration occurring during routine transoesophageal echocardiographic examination of the heart while intubated under general anaesthesia. Taurolithocholate-induced inhibition of biliary lipid and protein excretion in the rat.

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In this review, we give a critical overview of the different studies published up to now, and we discuss the endogenous regenerative potential of NSCs of the newborn brain when challenged by an HIE insult. DLBCL was frequent and phenotype heterogeneity appeared similar to observations in Western countries suggesting applicability of established intervention approaches. This non-stationarity leads to smoothed BAEPs when applying ensemble averaging or any other technique based on BAEPs stationarity. Surgical field obtained at the skull base can extend from the contralateral eustachian tube to ipsilateral geniculate ganglion.

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Identification of carbohydrate structures that bind human antiporcine antibodies: implications for discordant xenografting in humans. Patients in any of the following stages of chronic kidney disease: early, predialysis, and dialysis. Spatial analysis is increasingly important for identifying modifiable geographic risk factors for disease.

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We illustrate the methods with an analysis of mouse gene expression data measured over ten different tissues. Domestic activities and walking in the elderly: evaluation from a 30-hour heart rate recording. Peripheral blood leukocyte profiles showed increases in eosinophils and basophils with decreased monocytes in the GM-CSF arm.

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The oxybutynin transdermal formulation has been found to have side effects similar to that of a placebo in randomized controlled trials while providing excellent efficacy. Silicon nitride, one of the most important non-oxidic ceramic materials, is the binary parent compound of nitridosilicates, and it symbolizes the inherent material properties of these refractory compounds.

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Moreover, in K-ras activated mice, the expression of putative progenitor cell marker Dcamkl1 is upregulated in the glandular stomach. No partial seizure patients had normal sleep deprived EEGs and abnormal nap, but 29 of 57 had abnormalities or seizures only with sleep deprivation. Therapy of 645 children with parapneumonic effusion and empyema-A German nationwide surveillance study. From this analysis we derive necessary conditions for the formation of npsLBs on nanopore arrays by liposome fusion and discuss the limitations of the process as a function of nanopore geometry, lipid membrane properties, and surface interaction.

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Treatment of graft reinfection should include reduction of immunosuppression, and systematic exposure to alternative antivirals. This suggests that adherence intervention early in the course of treatment could play a role in improving long-term seizure freedom rates in children with epilepsy. In the present study we analyzed time-domain heart rate variability in coronary artery disease (CAD) patients with known thyroid diseases. We show that perceptually the relationship between parts is biased towards the conventional structural hierarchy in western music in which the melody generally dominates (leads) the accompaniment. This concurred with the observations that molecules involved in initial signaling events leading to germinal center formation were not altered (e.g., B7.2, CD40 and tumor necrosis factor R1).

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Herein we report a general strategy to synthesize highly uniform and monodisperse rare earth fluoride nanocrystals through a novel OA/ionic liquid two-phase system, while water-soluble hexagonal NaREF(4) nanocrystals are obtained by adding n-octanol. TFcP-functionalized ITO electrodes showed very high stability, and their application in photocatalytic oxygen activation has been tested. In addition we determined the allele frequencies of eight common single-nucleotide polymorphisms (SNPs) in the ATP7B gene. These findings constrain models of the cognitive mechanisms indexed by the ERN/Pe complex.

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Melanocytes and melanosis of the oesophagus in Japanese subjects--analysis of factors effecting their increase. Clinical Applications of NanoVelcro Rare-Cell Assays for Detection and Characterization of Circulating Tumor Cells. Although many studies have demonstrated that IL-1, TNF, and their mRNA are up-regulated in the CNS after injury, the functional roles of these cytokines in the injury are far from completely understood. Passive immunization significantly enhanced pulmonary clearance of the homologous strain in this model. WSM induces differentiation of rabbit BMSCs towards osteoblasts by increasing BMP-2 gene expression, in which process Cbfa1 gene does not seem to play a significant role.

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Evidence and mechanisms of immunosuppression in tick infestations. Cryosections of the brains were stained for Nissl substance to quantify brain injury. Eighty-two hyperprolactinaemic patients (75 women, seven men) diagnosed as having a prolactinoma on the basis of dynamic PRL function tests, radiological investigation and exclusion of other causes. The developed surgical robot has sufficient workspace to perform general MIS and has been shown to provide acceptable motion tracking control performance. Renal artery pseudoaneurysm (RAP) is a rare complication of partial nephrectomy, but is usually effectively managed with renal vessel embolisation.

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We propose a rapid, inexpensive, sensitive, odorless, less harsh, and in vitro methylation-free CBB stain. Recent research has elucidated three key concepts in our understanding of polycystic ovary syndrome. Our approach is esonix 20 mg prednisone based on the diffusion process approximation and the resulting mathematical expressions admit intuitive genealogical interpretations, which we utilize to introduce further approximations and make our method scalable in the number of loci. Gender roles and acculturation: relationships with cancer screening among Vietnamese American women. The aims of this study were to elucidate the clinical differences among patients with CBD stones who required and did not require emergent drainage, and to identify risk factors for the development of cholangitis requiring emergent drainage in patients with silent CBD stones.

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To evaluate the prevalence of urinary incontinence (UI) and its association with frailty among men aged 80 years and older in Taiwan. We find that, although certain cysteine substitutions diminish interaction with Gal80, those substitutions have little effect on the drug use evaluation of ciprofloxacina activating function in vivo and interaction with TATA box-binding protein (TBP) in vitro. Sprengel deformity (ie, congenital elevation of the scapula) is a rare clinical entity. Histology showed an extensive, well-differentiated angiosarcoma. Summary of the discussion on the practical use and comparison of new protocols for the dosimetry of high-energy photon and electron beams.

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Effects of 8-hydroxy-GTP and 2-hydroxy-ATP on in vitro transcription. Calculations of the band decomposed charge densities suggest that the deep black color of tropylium tin iodide is attributed to iodide ligand to tin metal charge transfer, while the bright red-orange color of tropylium lead iodide arises from charge transfer between iodine and tropylium states. Adenocarcinomas were sub-classified into four groups using two factors, the ratio of consolidation to the tumor diameter (C/T) and the dapoxetine fda approval 2014 toyota tumor diameter alone.

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Cyanobacteria have already been recognized to provide chemical and pharmacological novelty and diversity over conventional sources of drugs for combating major diseases ranging from AIDS to cancer. The decrease of the diagonal viscosity in magnetic field leads to negative magnetoresistance which is temperature and size dependent. A scanning electron microscope study acihexal 200 mg morphine of the luminal surface specializations in the blood vessels of the pecten oculi in a diurnal bird, the black kite (Milvus migrans).

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Polyacrylamide gel electrophoresis and determination of the number of SH-groups liberated in the course of reduction suggest that the observed inactivation is primarily due to the disruption of the S-S-bridge between the A- and B-chains of thrombin. The results obtained in our research demonstrated that, after a proper selection of patients and risperidone delusional parasitosis and schizophrenia lesions, and applying an adequate surgical technique, this type of biomaterial in the treatment of periodontal defects acts in an optimal manner as a filler inducing the formation of new bone as evidenced by histological examinations. The most familiar version is the Dali server, which performs a database search comparing a query structure supplied by the user against the database of known structures (PDB) and returns the list of structural neighbors by e-mail. The LOD score in the region increased to 4.1 when a subset of the sample was genotyped with the Illumina Linkage III panel for the Genetic Analysis Workshop 14 (GAW14). The effects of shape description methods (shape indices, Procrustes analysis and elliptical Fourier analysis) on classification performance were evaluated.

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In our study, the functional characteristics and membrane localization of OCT1 and OCT2 were investigated by uptake studies using MDCK cells transfected with rat OCT1 or OCT2 cDNA (MDCK-OCT1 or MDCK-OCT2) and immunological studies. The effects on the incorporation of uridine in nucleic acids of kidney, heart and brain were minimal. Precise assessment of blood cell kinetics in the pulmonary microcirculation is extremely difficult because pulmonary microvascular architecture contains arterioles, venules and capillaries in an exceedingly intricate and densely convoluted fashion. Both maxpedition remora gearslinger milspecmonkey review 360 complete and ongoing projects, along with their associated metadata, can be accessed in GOLD through precomputed tables and a search page. Here, we review recent major genetic advances in myeloid and lymphoid malignancies, the impact of these findings on prognostic models, our understanding of disease initiation and evolution, and the implication of genomic discoveries on clinical decision making.

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NET metastases that are CgA-positive/NKX2.2-negative would suggest a BP primary, daclatasvir dihydrochloride medicine whereas those that are CgA-positive/NKX2.2-positive would suggest a GI primary. This modified micropocket assay of corneal angiogenesis in rats demonstrated the stimulatory effect of several widely used topically delivered antiglaucoma medications on the angiogenic process. Clinical assessment of the effect of switch from immediate-release to extended-release methylphenidate in 181 patients with isolated attention deficit/hyperactivity disorder (AD/HD) or AD/HD associated with pervasive developmental disorder

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Higher order structure of (1,3)-beta-D-glucans and its influence on their biological activities and complexation abilities. Application of a two layer method of cultivation to determine the susceptibility of Trichophyton verrucosum by a standard plate diffusion test. fumigatus (6 x 10(6) CFU) teranex soap where to buy resulted in the induction of interleukin 18 (IL-18), tumor necrosis factor alpha (TNF-alpha), IL-12, and gamma interferon (IFN-gamma) protein in bronchoalveolar lavage fluid and/or lung tissue.