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Fulvicin (Griseofulvin)
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Griseofulvin

Fulvicin, an antifungal drug, has recently been shown to inhibit proliferation of various types of cancer cells and to inhibit tumor growth in athymic mice. Due to its low toxicity, Fulvicin has drawn considerable attention for its potential use in cancer chemotherapy. This work aims to understand how Fulvicin suppresses microtubule dynamics in living cells and sought to elucidate the antimitotic and antiproliferative action of the drug.

Other names for this medication:
Griseofulvin, Grifulvin, Fulcin, Fulvicin, Fulviderm, Fungistop, Grifulin, Grisetin, Griseofulvina,

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Lmcd1/Dyxin, a novel Z-disc associated LIM protein, mediates cardiac hypertrophy in vitro and in vivo. Half of the patients hospitalized in intensive care units have a central venous catheter (CVC) inserted. A limit-of-detection of 100 nM was demonstrated for Rhodamine 6G, and 10 microM for fluorescein. MiR-23 in the embryonic heart is required to restrict endocardial cushion formation by inhibiting Has2 expression and extracellular hyaluronic acid production. Colchicine prevents tumor necrosis factor-induced toxicity in vivo.

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