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Gladem (Sertraline)

Gladem belongs to a class of medications called selective serotonin reuptake inhibitors, or SSRIs. These medications work by increasing the level of available serotonin in the brain.1 Low levels of serotonin in the brain are linked to a depressed mood as well as other psychiatric symptoms.

Other names for this medication:
Sertraline, Chear, Daxid, Depsert, Gladem, Inosert, Lomaz, Serlift, Serline, Sertima, Zoloft, Zosert, Zotral,

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Pulmonary arterial hypertension (PAH) is characterized by a progressive increase in pulmonary vascular resistance caused by a proliferation of vascular endothelial and smooth muscle cells, resulting in occlusion of the lumen of small pulmonary arteries. A new light on T cell activation shed by a photoactivatable agonist. Age-related accumulation of mutations has been extensively documented, and it has been proposed as one of the prominent causes of malignancies in old age.

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Impaired regulation of natural killer cells in immunoglobulin synthesis by peripheral blood mononuclear cells from patients with ulcerative colitis. Health impact assessment of an urban regeneration project: opportunities and challenges in the context of a southern European city. Within the latter group, Spilocuscus is excluded from a Strigocuscus-Phalanger clade, which, in turn, is not fully resolved on a jackknife strict consensus tree. Tissue-engineered skin was fabricated using this asymmetric scaffold, fibroblasts, and a human keratinocyte line (HaCaT).

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The 2007 Nobel Prize for Physiology or Medicine was awarded to Mario R. Unusual sacral creases were found in 25/48 patients, a linear array of hemangiomas (nevus flammeus) on the back in 3/48, and limitation of supination in 5/48. We have established cell lines in which expression of wild-type Sp3 or a serine 73 to alanine (S73A) mutant is controlled by tetracycline. Feeding pregnant rats a protein-restricted diet persistently alters the methylation of specific cytosines in the hepatic PPAR alpha promoter of the offspring. Multiple micronutrient supplementation with Sprinkles powder and crushable Foodlets tablets may be effective means of controlling micronutrient deficiencies in infants.

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These preliminary data reveal that reduction in right caudate activation may be a neural mechanism of weight loss in BWL, and baseline FTO variant and reduction in frontostriatal activation during BWL predict short- and long-term weight loss. Time spent on work activities is primarily used for health education, promotion, moving between households, and direct patient care.

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The goals of the study were to determine what may hinder the efficacy of a PEP for knee OA by determining the relevance of depression, pain, disease knowledge and physical ability in patients to their response to a PEP. Evaluation of hormonal changes in menstrual cycle of women infected with pulmonary tuberculosis in Nnewi, south eastern Nigeria. capitalizing on joint information among modalities) is still remarkably small given the known benefits. Evidence for the close linkage between lymphocyte cytosol polypeptide with molecular weight of 64,000 (LCP1) and esterase D.

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This study arose out of a concern about the transmission of infectious diseases through eye splash injuries in surgery. There is a need to develop and enforce evidence-based protocols and guidelines for use in the management of patients with TBI in sub-Saharan Africa. These levels declined rapidly in three desensitized patients who were studied in contrast to the slower decline in three patients who were not desensitized. The island sign is a reliable CT imaging marker that independently predicts hematoma expansion and poor outcome in patients with ICH.

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Highly divergent gene expression programs can lead to similar chordate larval body plans. Urinary bisphenol A and hypertension in a multiethnic sample of US adults. These data, together with the observation that successful antiestrogen therapy is associated with reduced expression of RI mRNA, suggest that targeting R subunits is an appropriate therapeutic strategy for breast cancer. CXCL4-induced migration of activated T lymphocytes is mediated by the chemokine receptor CXCR3.

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Evaluation of Inflammatory Response to Endodontic Sealers in a Bone Defect Animal Model. No-take marine reserves (NTMRs) provide hope that local carrying capacity may be partially restored if reserves are protected long enough. Diagnosis by numbers: defining skin disease pathogenesis through collated gene signatures. Heparan sulphate, chondroitin-6-sulphate, and versican displayed dynamically changing distribution patterns. This animal model implies that exogenous carnitine supplementation may be helpful in preventing free oxygen radical damage and inflammatory reactions in liver tissue.

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Furthermore it is stressed that only the histopathological examination gave the correct diagnosis and permitted the definitive hormonal treatment. Newcastle disease (ND) is a serious neurological and respiratory disease of poultry that affects all types of birds but has traditionally not caused symptoms in wild aquatic birds, the natural hosts. Chemotherapy with or without radiotherapy is the mainstay of treatment for primary central nervous system lymphoma (PCNSL).

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Isolated rupture of the right hemidiaphragm with eventration of the liver demonstrated by liver scan. Optimizing the shave excision technique to aid accurate histological diagnosis.

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Coronary venous EAM was performed intraprocedurally and integrated with DE-CMR to guide LV lead placement in real time. Total anomalous pulmonary venous drainage with major aorto-pulmonary collaterals - a diagnostic dilemma. The patient was admitted for cardiac monitoring, and electrocardiogram returned to normal upon discontinuation of methadone.

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Films of 10 nm thickness produced so much type II electrons that identical images were obtained with the conventional SE-II and BSE-II signals. Potential of fluorescence spectroscopy for the characterisation of maple syrup flavours.

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There is new indirect evidence that the elaboration of endogenous opioids may modulate dyspnea intensity during exercise in COPD. Immunohistochemical characterization showed positivity for NK1/C3, neuron-specific enolase, and alcian blue. The hypothesis on the lipogenic insulin functioning is confirmed by specific knockout of Insr gene in only tissue: muscles, adipose tissue and other, and by the restoration of its expression in transgenic mice. These differences were found for both observer ratings and self-report. Long non-coding RNAs (lncRNAs) are new research hotspots for their vital roles in regulating gene expression.

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Tetraspanins (tetraspans or TM4SF) are a family of integral membrane proteins with four transmembrane helices, a small extracellular loop, and a large extracellular loop. DIT disorders can be a consequence of decreased platelet production (bone marrow suppression) or accelerated platelet destruction (especially immune-mediated destruction). There were also less severe renal morphologic changes in the former three groups vs the ADR controls. We show that TGF-alpha mRNA and protein are hypoxia-inducible in VHL(-/-) RCC cells expressing reintroduced VHL. Placebo effect model in asthma clinical studies: longitudinal meta-analysis of forced expiratory volume in 1 second.

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Alveolar soft part sarcoma: clinical course and patterns of metastasis in 70 patients treated at a single institution. While it is generally believed that structural brain damage induced by METH results from oxidative stress, in this work we present data suggesting robust disruption of blood-brain and blood-spinal cord barriers during acute METH intoxication in rats. Cationic liposome-mediated gene transfer to tumor cells in vitro and in vivo. We studied bone-mass status in 10 patients (seven males, three females, age 19-66 years) who had been receiving HTPN for 0 to 67 months (mean 24 months), mostly for short-bowel syndrome.

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Numb is involved in the non-random segregation of subcellular vesicles in colorectal cancer stem cells. In this experiment, green-synthesized silver and gold nanoparticles were produced rapidly by treating silver and gold ions with an extract of Memecylon umbellatum leaf. Questions on perceived barriers on regular exercise and walking habit were also included in the questionnaire. Since tissues are in semisolid-state, their high-resolution (HR) spectra cannot be obtained by conventional NMR spectroscopy. Each of the three eznymes has been purified by means of protamine sulfate precipitation, ion exchange chromatography, affinity chromatography, and velocity sedimentation.

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Other recent advancements in surgical technique, such as biaxial microincision surgery, result in similar ECL rates to that of standard phacoemulsification. Use of Prophylactic Antibiotics in Mechanically Ventilated Patients With Burn Injuries. The calculated Klw values from the two QSPR agree nicely with the observed values and with one another. Diseases of teeth, periodontium and oral mucosa as side effects of anticholinergic drugs

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The mean ratio of the proximal extent was 0.55 in the midline and the lateral angular extent was 66 degrees. Castrated males had reliably lower attractivity than normal females on all indicator responses shown by the tethered males. The release of nitrites in kidneys from hypertensive rats was lower than that in kidneys from normotensive rats.

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In this report, we investigated the molecular mechanisms underlying FGF-2 mediated osteogenic inhibition, demonstrating that addition of exogenous FGF-2 to mASCs antagonizes upregulation of BMPR-IB gene expression in response to retinoic acid. A decrease in platelet 5-HT reuptake may bear implications for our understanding of poststress adaptive changes in the cardiovascular system as well as in the central nervous system (CNS) serotonergic neurones following stressful stimulation. The right IIA was ligated and the inferior mesenteric artery was reimplanted. Implants subsidence is a frequent complication of interbody fusion, which can result in pain, deformity, nerve damage, and even failure of surgery. We sought to characterize maternal risk profiles and severe maternal morbidity at low-volume hospitals in the United States.

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RBR (RING1-IBR-RING2) proteins play an important role in protein ubiquitination and are involved in many cellular processes. In a situation in which the difference in effects on disease morbidity and mortality of different treatment options for these malignancies is likely to be small, the quality of life and psychological aspects may be decisive in treatment choice. Earlier, AstraZeneca withdrew regulatory filings for non-small cell lung cancer (NSCLC) in the US and EU, and later discontinued development. We herein set out to review the literature regarding the relations between cancer chemotherapy, radiation treatment, and Clostridium difficile-associated colitis.

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Most studies have focused on identification of resistance mutations, leaving one to speculate on the fate of these mutants once the antibiotic selective pressure is removed. Main reasons of imperfect laboratory diagnostics were revealed, such as, low sensitivity of bacteriologic test, nonobservance of existing recommendations on diagnostics of Yersinia infections, performing of single but not repeated serologic test, absence of necessary laboratory equipment. Nanocrystalline silver (Acticoat) for itch relief in the burns patient. Analysis of the accumulation of mutants in Sabin attenuated polio vaccine viruses passaged in Vero cells.

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Traces of various carbon sources in saline triggered the development of a novel small resting cell (SMRC) morphotype. Neural network analyses show that cognitive features found in insects, such as numerosity, attention and categorisation-like processes, may require only very limited neuron numbers. A mathematical model of vasoreactivity in rat mesenteric arterioles: I. Although younger patients are supposed to be less susceptible to bleeding complications of mechanical aortic valve replacement (mAVR) than older patients, there is a relative paucity of data on this subject. There is, however, a concomitant decrease in BMD and S-calcium, and an increase in fP-PTH.

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Repulsion of cerebellar granule neurons by chondroitin sulfate proteoglycans is mediated by MAPK pathway. However, since calibration of a LMW heparin standard against the IS would give potencies that differ widely by the different assay methods, a single assay method such as the anti-Xa amidolytic, plasma, would need to be chosen for this calibration. More than half of primary care providers are prescribing medications to children with bronchiolitis. Meatal skin preservation without circular meatal flap incision is recommended to avoid postoperative canal stenosis. Basic research is an important component of acupuncture medicine, and is also the driving force for improving clinical practice.

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High-dose dobutamine stress magnetic resonance (DSMR) is a well-established imaging technique for the detection of coronary artery disease (CAD). Within each of the three major drug classes, the more sedative members of the class tended to have relatively greater effect on anxiety and the less sedative tended to have relatively greater effect on depressive mood components of the symptom picture.

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In the RuPc-PDI conjugates, substitution with ferrocenes produces a slight acceleration of the charge separation upon photoexcitation of the PDI chromophore. Vitamin D insufficiency contributes to calcitriol (1,25D) reduction in chronic kidney disease (CKD).

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The feasibility of such a high urine output has been tested and confirmed. This article discusses how cognitive processing is related to medication errors.

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Curricular focus on HF can strengthen teacher identity, improve teacher evaluations, and promote surgery as a career choice. A standardized protocol was used with a catheter placed at the mid-part of the popliteal artery, and a total of 9 cc of non-ionic iodinated contrast material was injected at a rate of 3 cc/sec.

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Thus, TCR-CD3 clustering translates antigen recognition by the TCR into signal initiation by the CD3 complex, and the formation of dense signaling-competent clusters is a process of antigen discrimination. To the best of our knowledge, this is the first report that describes the resolution of LV thrombus with apixaban treatment in a patient with hypertrophic cardiomyopathy. Parent of origin effects were present, with linkage primarily observed to paternally derived alleles. To investigate in vitro cytotoxicity and oxidative stress response induced by multiwalled carbon nanotubes (MWCNTs).

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The floating loop was able to decouple the elements over 20 dB for both frequencies. Vitamin K antagonists are mostly used for secondary prevention of venous thromboembolism and for primary prevention of arterial embolism in patients with permanent atrial fibrillation or with cardiac prosthetic valve. Data from the National Health and Nutrition Examination Survey (NHANES III, 1988-1994) conducted by the National Center for Health Statistics of the Centers for Disease Control and Prevention.

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A prospective observational study was conducted at four hospital transfusion services to test an alternative paradigm of identifying xHEA-typed units for patients in three cohorts by utilizing DNA analysis and a novel inventory management model. Moreover, PKC-dependent down-regulation of DAT does not correlate with the phosphorylation state of several well-studied MAP kinases (ERK1/2, p38, and SAPK/JNK).

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We propose that this specific organization could result from the constraints of accommodating the replication and transcription initiation processes at chromatin level, and reducing head-on collisions between the two machineries. The difference in the acetabular component orientation between the two positions, which might be caused by the difference between intra- and postoperative pelvic orientation, should be considered during THA. Although the EVI analyses suggested substantial expected net benefit from a large, multicentre randomised controlled trial (RCT) evaluating the clinical effectiveness of IVIG, the remaining uncertainties around the design of such a study mean that we are unable to recommend it at this time.

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Acute myocardial infarction (AMI) is accompanied by electrophysiological changes in cardiovascular system as well as those in autonomic cardiac control. The inhibitory effects of DW A2114R on the cell growth and the colony-forming ability were about 1/10 and 1/10-1/30, respectively, of the CDDP dose. People living with HIV represent a subgroup with a significantly elevated prevalence of cigarette smoking. Compared to Scansite, SMALI exhibited improved accuracy in identifying binding peptides for SH2 domains.

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Foundations for modeling the dynamics of gene regulatory networks: a multilevel-perspective review. brucei rhodesiense are vector-borne pathogens that cause sleeping sickness also known as Human African Trypanosomiasis (HAT), which is fatal if left untreated. The ADC values calculated from standard b-value DWI were significantly higher than those calculated from high b-value DWI. We aimed at assessing the factors that can influence results of the dissemination of an already validated, new generation commercial Point-of-Care Test (POCT) for detecting celiac disease (CD), in the Mediterranean area, when used in settings where it was designed to be administered, especially in countries with poor resources. Despite this overlap of the projection neurons, only an occasional double labeled neuron was observed in area TPO.

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Sixty-six patients with MS (28 with relapsing-remitting MS, 22 with secondary chronic progressive MS, and 16 with primary chronic progressive MS) and 16 control patients receiving corticosteroids for other disorders were included in the study. In the catecholaminergic-containing N2a cells, fructose dose-dependently upregulated the expressions of glucose transporter 2 and 5 (GluT2, 5) and the rate-limiting enzyme of fructolysis, ketohexokinase (KHK), leading to the increases in pyruvate and ATP production, as well as the release of the neurotransmitter, dopamine. Mutagenesis of adeno-associated virus type 2 capsid protein VP1 uncovers new roles for basic amino acids in trafficking and cell-specific transduction. Viral load was significantly different between susceptible and resistant strains but not between intermediate and highly susceptible strains.

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Expression of angiogenic and lymphangiogenic factors by tumours may influence the route of metastatic spread. The melting temperature of gels was nearly unchanged with varying salt concentration, but the melting enthalpy decreased monotonically with salt addition.

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This study evaluates the impact of BMI training on improving DM self-management. Implantable cardioverter defibrillator undersensing leading to delayed or aborted therapy delivery has been reported with induced arrhythmias and following failed defibrillator shocks. The extraction techniques were studied by multi-index test experiment formula evaluation and orthogonal design, which took change of peak area in HPLC fingerprint of active part for Vernonia anthelmintica as indices. Pharmacy students completed a validated survey instrument, Attitude Toward Healthcare Teams Scale (ATHCTS) prior to and after course participation.

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Inhibition of CD39 enzymatic function at the surface of tumor cells alleviates their immunosuppressive activity. Changes in serum concentrations of beta-carotene and changes in the dietary intake frequency of green-yellow vegetables among healthy male inhabitants of Japan.

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(3) Changes of the Southern land pattern were found in some families of some transformants, especially, in the two families of Ding 4R5. Targeted Smart pH and Thermoresponsive N,O-Carboxymethyl Chitosan Conjugated Nanogels for Enhanced Therapeutic Efficacy of Doxorubicin in MCF-7 Breast Cancer Cells. We suggest that direct transfection with PCR amplified genes can be a simple and useful approach for optimization of electropulse-based transfection not only of Kasumi-1 cells, but also may be useful for other cell lines that are difficult to transfect in suspension. In the present study, adult Eurasian marsh frogs, Pelophylax ridibundus, and water samples were collected from a reference lake and three water bodies in central Anatolia, Turkey, to evaluate the water for chemical pollutants and possible effects metronidazole 200 mg antibiotic of pollutants on the DNA of frog erythrocytes by using a comet assay.

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Simultaneous preconcentration of toxic elements in artificial saliva extract of smokeless tobacco product, mainpuri by cloud point extraction method. They were amitriptyline 10 mg effet secondaire du studied during the index admission and followed for a year to identify any patients who were readmitted as an emergency with a diagnosis of deep venous thrombosis or pulmonary embolism. Use of DB-1 capillary columns in the GC/FID analysis of benzoylecgonine. Transcription of the murine thymidine kinase gene, which is coregulated with the G1/S phase transition, is activated by changing the binding of protein complexes Yi1 and Yi2 to three upstream DNA motifs.

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Studies were initiated to localize the C-reactive protein (CRP) binding site on the collagen-like region (CLR) of C1q. As a result, it was demonstrated the multiplication capacity of the NCI-H292 line lanx aspen fda food for Adenoviruses 3 and 7 and parainfluenza 3, being more useful for their multiplication than the traditionally used lines. By using the calendar-time-information-time transformation, information fractions corresponding to desired calendar times can be determined. Hydroxyapatite is a biocompatible material for augmentation of edentulous ridges to improve patient comfort and denture stability. Besides, Oroxylin A could obviously radiosensitize ESCC cells by arresting tumor cells in G2/M phase and regulating cyclin B1 and Cdc 2 protein expression.

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AFA can be readily detected by citrullinated peptides in an LIA-based test, resulting in high specificity and positive predictive value for RA. Differential ganciclovir-mediated cell killing by glutamine 125 mutants of herpes simplex virus type 1 thymidine kinase. To evaluate the antimicrobial effect of the ozonized sunflower oil griseofulvin dosing instructions (Oleozon) on different bacterial species isolated from different sites.

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B7-H4 mRNA and protein level were significantly higher in UCC tumor tissues compared with rx information for tamsulosin adjacent nontumor tissues as assessed by qRT-PCR and immunohistochemical staining, respectively. These metabolites can be used as chemical markers for taxonomic studies.

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Have sperm counts deteriorated over the past 20 years in healthy, young Japanese men? It is a prospective case series study done in the National Cancer Institute from April 2000 to May 2009. Fast dissolving tablet containing domperidone ternary solid dispersion was developed to improve the dissolution of bicalutamide 50 mg mylan 477 drug and stability of solid dispersion.

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To study the characteristics of subclinical autonomic nervous dysfunction in de novo PD without orthostatic hypotension (OH). Dopamine (DA) turnover in the ME was not significantly affected by the presence of the hGH gene, suggesting that the difference in plasma PRL levels between normal and transgenic mice is mediated through changes in PRL-regulating factors other than DA. The model allows examination of acute and chronic changes of local cerebral blood flow (lCBF) and reserve capacity in correlation with 225 mg venlafaxine hydrochloride behavioral parameters. Thirty minutes later, a continuous infusion of LPS (1.7 mcg/kg/h) was started. To determine the Australian native ant species associated with ant sting anaphylaxis, geographical distribution of allergic reactions, and feasibility of diagnostic venom-specific IgE (sIgE) testing.

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The real ecological fallacy: topiramato 100 mg tablets apple epidemiology and global climate change. Without the safety and effective vaccine for HIV the HIVvoluntary counseling testing (VCT) has been documented as a central component ofcomprehensive HIV prevention strategies targeting individual risk reduction by modified high risk behaviors. TgBCP1 is essential for cyst formation and is the first example of a developmental regulation in translation initiation site preference for a T. Polymerase chain reaction and gene sequencing analysis confirmed bla(GES) genes identified in three P. Effect of periwinkle alkaloids in idiopathic thrombocytopenic purpura.