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Ladialis under the name of Ladialis is used to treat erectile dysfunction (impotence) and symptoms of benign prostatic hypertrophy (enlarged prostate). Another brand of Ladialis is Adcirca, which is used to treat pulmonary arterial hypertension and improve exercise capacity in men and women.

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Morphometric information of the brain vascularization is valuable for a variety of clinical and scientific applications. Ventricular tachycardia around the tricuspid annulus in right ventricular dysplasia. Training creative cognition: adolescence as a flexible period for improving creativity. Over the first two years of implementation of this curriculum, we have observed that it takes no more faculty time to supervise resident preparation and presentation than it would for the faculty to prepare and present material concerning similar curriculum objectives in a lecture or conference format. Bacterial cell products signal to mouse colonic nociceptive dorsal root ganglia neurons.

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Especially noteworthy, the prepared Con A-invertase-CaHPO4 hybrid nanoflowers simultaneously loaded sufficient invertase and enhanced the activity of the immobilized invertase, which fits well with the requirements of signal labels for bioassays. Divalent metal phosphonate coordination polymers constructed from a dipiperidine-based bisphosphonate ligand. Patients with ovarian vein thrombosis (1990-2015) and age- and gender-matched patients with contemporary leg deep vein thrombosis (DVT) were assessed for differences in etiology, venous thromboembolism recurrence, and survival in a case-control study.

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Pharmacodynamic target evaluation of a novel oral glucan synthase inhibitor, SCY-078 (MK-3118), using an in vivo murine invasive candidiasis model. UV irradiation resulted in a quick release of the inclusion compounds (within 1 min in most cases) under simulated physiological conditions. More recently, another biomarker, the neuroblastoma rat sarcoma viral oncogene (NRAS), was found to be as valuable for the refinement of this targeted therapy.

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Adjustments for confounders substantially modified the relationship between state anxiety and cognitive performance. Thus, replacement of a Pro in the interior of an alpha helix can have substantial effects on protein stability. Conduction block in hereditary motor and sensory neuropathy type I.

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273, 8389-8397), signals regulating spontaneous neutrophil apoptosis have not been fully determined. Cytological method of examination in the diagnosis of certain diseases of the distal portion of the large intestine A new synthetic route to the electron-deficient ligand tris(3,4,5-tribromopyrazol-1-yl)phosphine oxide.

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Diagnostic applications of CT for scaphoid non-union include the determination of the exact location of the fragments and the evaluation of post-traumatic cysts, thus simplifying pre-operative planning. Higher serum concentrations of this steroid may reduce the risk of autism. The epidemiological data, combined with pathological and immunological data, may contribute to the debate whether MS is an autoimmune disease, a latent or persistent viral disease, or a neurodegenerative disease.

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However, the link between these compounds and CRC remains unknown. BmK CT modification increased the cellular uptake of dendrimers in C6 glioma cells, but not in the normal RLE-6TN cells. The expression and secretion of MMP-2, MMP-9, TIMP-1, TIMP-2 and the DNA-binding activity of NFkappaB in normal endometrial stromal cells or in co-cultures with normal or endometriotic epithelial cells from patients with endometriosis. The MTT assay and the flow cytometry assay were performed respectively for cell proliferation and apoptosis after the treatment with OA for 48 h. The objective of this study was to describe the opinion of a group of postpartum women about compliance with the Ten Steps in a hospital with the intention to be certified as a Baby Friendly Hospital.

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The Need to Improve Care and Research on Sexual Functioning in Cardiology. Techniques for infrarenal aneurysm repair have reached a plateau. Load reducing mechanisms, such as a decreased midstance knee flexion angle, identified by others in subjects with endstage knee OA or reduced external flexion or extension moments were not present in this group of subjects with knee OA who were being managed by conservative treatment.

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Our initial focus on differences in setting did not explain our mixed results. Video-based skill assessment of endoscopic suturing using the pediatric chest model and a box trainer distinguished pediatric endoscopic surgeons according to their clinical experience, and pediatric-specific skills were identified.

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To offer clinical suggestions for therapy in patients at risk for veno-thrombotic events. The applicability of the new CFD code for quantifying the shear stress on a flexible leaflet is thus demonstrated. Despite repair, MR progresses in many patients and is associated with poor survival, although more detailed prospective data are needed to characterize this relationship.

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All trisomies 13, 18 and 21 and all cases with gonosomal aberrations were detected by FISH analysis with the exception of one case of trisomy 21 in which hybridization failed due to technical problems. A Q-switched Nd:YAG laser utilizing UV-illuminated LiNbO(3) was shown to operate under cold temperatures without prelasing or spatially variable loss. If the pre-test probability is above the test-treat threshold, empirical treatment is justified, because even a negative Xpert will not lower the post-test probability below the treatment threshold. These findings suggest that defects in the same gene may result in different degrees of phenotypic alterations. This process, which we have named reverse transformation, appears to offer considerable hope in the treatment of a large number of malignancies.

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This paper reports a literature review, focused in Chile, on the magnitude, impact, recommended management strategies and new research on depression. Quantitative ultrasonic measurements were made in a series of patients and show a statistically significant difference between the acoustic reflectivities of the separated retina in retinoschisis and retinal detachment.

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IL-17A knockout mice and wild-type mice were inoculated systemically (intravenously) or locally (intra-articularly) with S. Only 3 cases of chronic norovirus infection in adult solid organ transplant recipients have been reported thus far. The purpose of this study was to evaluate the effect of decompressive craniectomy on ICP and cerebrospinal compensation both within and beyond the first 24 hours of craniectomy. The anamnestic antibody response appeared to be stronger in poults that had low antibody titers prior to challenge-exposure to VVNDV.

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Growth/no growth interfaces of table olive related yeasts for natamycin, citric acid and sodium chloride. Higher temperature and lower food level had an adverse effect on M. Whole genome-based assessment of the taxonomic position of the arthropod pathogenic bacterium Rickettsiella grylli.

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We have shown the usefulness of the heteroduplex mobility assay (HMA) for phylogenetic analysis and for the discrimination of closely related Colletotrichum species. While the three short covalent bonds typical to pnictogens are characteristic in both liquid and clusters, the number of large voids and the total cavity volume is much larger in the liquid at 1023 K, with larger local concentration variations. Alteration of substrates in this way often leads to proteasomal degradation mediated by the von Hippel-Lindau Tumor Suppressor protein (VHL) containing E3-ubiquitin ligase complex known as ECV (Elongins B/C, CUL2, VHL). During the hospitalization, temperature normalized and the skin lesions disappeared after 3 weeks of treatment.

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Cox regression analysis with adjustments for age, gender, hypertension, body mass index, established cardiovascular disease and total cholesterol was used to estimate hazard ratios for fatal ischemic heart disease. Subsequent early pregnancies outcome following complete hydatiform molar pregnancy. Uterus transplantation is the youngest solid organ transplantation described in the literature.

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Psychometric properties examined include reliability, and construct and concurrent validity. Expanding the view on the evolution of the nematode dauer signalling pathways: refinement through gene gain and pathway co-option.

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Here we test the model by constructing strains that switch using two different mutant P cassettes introduced at the donor loci, mat2 and mat3. We previously reported that tumor necrosis factor-alpha converting enzyme (TACE) was specifically inhibited by TIMP-3 but not TIMP-1, -2, and -4. Long-term incidence of contralateral primary hernia repair following unilateral inguinal hernia repair in a cohort of 32,834 patients. Short report: hepatitis b infection and severe Plasmodium falciparum malaria in Vietnamese adults.

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We have found that the electrical conductance decreases and the threshold voltages shift in a positive gate voltage direction, as electrical characteristics are measured repeatedly. Physical activity, exercise and low-grade systemic inflammation. Bupropion SR was effective for smoking cessation among African Americans and may be useful in reducing the health disparities associated with smoking. The myocardial fibrosis degree was detected using Masson staining. A distinct stratum corneum antigen in psoriasis and its reactions with stratum corneum autoantibodies.

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We report a case of an 81-year-old man with bacterial myocarditis presenting with elevated troponins and sepsis, who succumbed due to a ruptured ventricle. A 1,3,4-thiadiazole library was constructed by solid-phase organic synthesis.

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Risk Indicators for Periodontitis in US Adults: NHANES 2009 to 2012. Specifically, we hypothesize a buffering effect for employees with high self-esteem and high quality of work life, and an exacerbating effect for employees with low self-esteem and low quality of work life.

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Supercapacitors can store and deliver energy by a simple charge separation, and thus they could be an attractive option to meet transient high energy density in operating fuel cells and in electric and hybrid electric vehicles. Direct migration of the protonated amine group is far more favorable (10.4 kcal/mol) and therefore presents the most likely candidate for the actual enzymatic reaction. However, no study to date has documented any effect of DMARD initiation based on MSUS findings (subclinical arthritis) alone.

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Inorganic nanomaterials are often key components in transducing light into drug delivery events. Lagged lower income position and its associations with health suggest that socio-economic disadvantages accumulate over time. Dengue hemorrhagic fever complicated with acute idiopathic scrotal edema and polyneuropathy. Perceived impact of environmental barriers on participation among people living with spinal cord injury in Switzerland.

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Restoration of elbow function in traumatic brachial plexus injury patients remains the priority in the reconstruction of the involved extremity. A system to simulate and reproduce audio-visual environments for spatial hearing research. Impact of pacing and high-pass filter settings on ventricular bipolar electrograms in implantable cardioverter defibrillator systems. The biliary microbiota had a comparatively higher similarity with the duodenal microbiota, versus those of the other regions, but with a reduced diversity.

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Comparative study of clones from isolates methicillin-resistant Staphylococcus aureus prevalent in Argentina The HPV E2 protein plays a critical role in this tethering by binding simultaneously to the viral genome and to chromatin during mitosis. Herein, we tested the hypothesis that regular endurance exercise (EE) improves the HF diet-induced impairment of carnitine status through stimulating the expression of hepatic genes involved in carnitine synthesis and uptake. Crocidolite exposure of RLE-TN cells also increased production of H2O2, a response that was inhibited by the mitochondrial respiratory chain inhibitor thenoyltrifluoroacetone (TTFA).

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Injection drug use (IDU) remains a major risk factor for HIV-1 acquisition. Here, we explore for the first time how this approach can be applied to a specific biological system, the human kinetochore, which is a multi-protein complex involving over 100 proteins. This study aimed to determine the true sensitivity and specificity of LBP in thyroid FNAC by meta-analysis. Considering risks of IMA ligation under dual antiplatelet therapy, increased blood pressure after TAVI, and general anesthesia, we performed combined TAVI and IMA ligation. The present work explores how the local structure of the control landscape influences the effectiveness and efficiency of quantum optimal control search efforts.

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Chemistry, Pharmacy and Other Allied Subjects-Resorcinol-A Delicate Test for Albumin in Urine. Thirty professionals from different organisational levels were selected, allowing for differences in ages, gender, length of working experience, and profession or education.

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Contractility of renal cortex following complete ureteral obstruction. Highly similar IgE variable regions were found after four years of allergen exposure in the same and in genetically non-related individuals. Network-wide deliberations were then brought to local constituencies for final decision making. All gastric biopsy specimens revealed normal mucosa or non-atrophic gastritis.

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Relationship between equol producer status and metabolic parameters in 743 Japanese women: equol producer status is associated with antiatherosclerotic conditions in women around menopause and early postmenopause. It is assumed that a latent BHV-4 infection was activated after application of dexamethasone and that the leucocyte fraction of the blood represents one site of latency of BHV-4 in cattle. A single base substitution in the variable pocket of yeast tRNA(Arg) eliminates species-specific aminoacylation. Effective extraction and purification of beta-xylosidase from Trichoderma koningii fermentation culture by aqueous two-phase partitioning. Ultrasensitive, and previously validated, piezoresistive force sensors were placed in lumbar facet joints of L3-4 and L4-5.

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The solubilized iron from the ferric core could then be transported across the lysosomal membrane back into the cytosol. The Hispanic Established Population for Epidemiological Studies in the Elderly (H-EPESE) project, a longitudinal population-based cohort study. The first step in the CHELS method is to establish the HELS formulations based on a finite number of acoustic pressure measurements taken on or beyond a hypothetical spherical surface that encloses the object under consideration. Examination of females in our isolated study population revealed a discrete polymorphism in female genitalia. Adipose-derived stromal/stem cells (ASC) are multipotent with abilities to differentiate into multiple lineages including connective tissue and neural cells.

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Comparison of the mutation scores of early and late-stage-enriched subgroups identified 358 genes that carry significantly higher mutations rates in the late stage subgroup. The application of intraarterial cooling did not provide a significant improvement in the protection of the NVB in this small study. This core set of drug targets have been analyzed for pathway annotation to identify 67 proteins involved in unique bacterial pathways. Hematuria resulting from urethral traumatic catheter insertion and removal is often encountered.

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The proportion of subjects exhibiting signs of evaporative dry eye resulting from MGD far outweighs that of subjects with pure ADDE in a general clinic-based patient cohort. The comparison of these clinical data with those previously obtained using a human osteotropic breast cancer cell line highlighted an overlapping group of proteins. Itch is broadly categorized as histaminergic (sensitive to antihistamines) or nonhistaminergic. The noncovalent functionalization of single-walled carbon nanotubes (SWNTs) is important in the development of advanced materials and nanoelectronic sensors and devices. The sonographic examination of renal allografts may detect vascular complications and peritransplant fluid collections, both of which may impair allograft function.

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Here, we report a case of PCI which was found during the treatment with lactulose therapy in a patient with liver cirrhosis and hepatic encephalopathy. Investigate changes in calciotropic hormones, IGF-1, body composition, and their associations with bone metabolism in adolescents. Unstimulated cells or cells preincubated with oxLDL or non-oxidised (n)LDL were treated with Nicotinic acid or Nicotinamide. Increasing numbers of reports over recent years highlight potential immunosuppressive mechanisms that act in tumors and systemically in cancer patients to block effective anti-tumor immune responses.

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Costal diaphragmatic length was measured in vivo, and the length at which maximal twitch force is generated was determined on muscle strips in vitro. This article describes briefly what biotech drugs are, why it has been necessary to regulate them differently, the evolution of the regulatory framework in Mexico, and the general features of the new system. About one-fourth of children and adolescents with epilepsy are dissatisfied with treatment.

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Early loss to follow up after enrolment in pre-ART care at a large public clinic in Johannesburg, South Africa. Nature of deposits in a tubular membrane oxygenator after prolonged extracorporeal circulation: a scanning electron microscope study. The average shearing strength for compact bone is about 10,000 psi. He or she will also be afforded an opportunity for practice expansion, particularly as an expert consultant, into other areas of immune inflammation, such as autoimmunity and graft rejection.

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These data suggest a potential role of nVDR and corticosterone in the regulation in adipocyte responses to 1alpha, 25-dihydroxyvitamin D and dietary calcium. Higher ABSM, defined as greater average house value or household income, were positively associated with the number of observed melanoma cases per ZIP-code.

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Ghrelin is a peptide that regulates maternal appetite and energy expenditure as well as playing a role in fetal nutrition. A new method of evaluating the degree of stenosis using the pressure loss coefficient is presented here. There was no history of trauma, cold injury, or similar lesions elsewhere in her body.

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The opportunity for stereotyped interaction may be the only aspect of a contingent stimulus that makes it a reinforcer for appropriate behavior. Proteins that belong to the protein phosphatase 1 and actin regulator (phactr) family are involved in cell motility and morphogenesis. In this review we discuss some important parameters associated with growth factor therapy and present an overview of selected preclinical studies, followed by a conceptual description of both established and proposed delivery strategies meeting therapeutic needs.

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elegans mutants and subsequent screens to identify interacting genes can proceed very quickly in this model organism. Hippocampal chemical anatomy in pediatric and adolescent patients with hippocampal or extrahippocampal epilepsy.

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Two months later, several nodules were found in his lungs, which were identified as metastases from the primary renal tumor that had been removed with the diseased kidney 8 years earlier. We are also investigating how the pluripotency of undifferentiated stem cells is regulated. These results show that activin B may promote BMSC-mediated wound healing by inducing actin stress fiber formation and BMSC migration via the ERK and JNK signal pathways. The literature review revealed 16 papers reported between 1952 and 2016.

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Outcomes after out-of-hospital cardiac arrest treated by basic vs advanced life support. Mammalian genomes encode two genes related to omeprazole 40 mg cause gout the TATA-box binding protein (TBP), TBP-related factors 2 and 3 (TRF2 and TRF3). Specifically, we integrated mutations, gene expression, DNA copy numbers, DNA methylation and protein abundance, all available in The Cancer Genome Atlas (TCGA) and developed iDriver, a non-parametric Bayesian framework based on multivariate statistical modeling to identify driver genes in an unsupervised fashion. PFGE and multilocus sequence typing (MLST) genotypes, antibiotic susceptibility patterns, the presence of enterococcal surface protein (esp) and hyaluronidase (hyl) genes and conjugation frequencies were determined.

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Age-related increase of superoxide generation omeprazole magnesium oral in the brains of mammals and birds. The robot used the image message and force signals to sense the different operation states and to prevent potential cortical penetration in the pedicle screw insertion operation. Food intake and energy expenditure are tightly regulated by the brain, in a homeostatic process that integrates diverse hormonal, neuronal and metabolic signals. Penicillin acylase-catalyzed ampicillin synthesis using a pH gradient: a new approach to optimization.

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CTLA-4 is therefore the first known substrate for Rlk suggesting the possibility that this kinase may participate in CTLA-4 function. Here, we show that yeast Elg1 interacts physically and genetically with PCNA, in a manner that depends on PCNA modification, and exhibits preferential affinity tegretol cr 200 mg carbamazepine tegretol for SUMOylated PCNA. We created a classic scoring system, a nomogram, and a boosting (i.e., machine learning) algorithm and calculated their accuracy by receiver operating characteristic analysis. Brownian dynamics simulations emulate the propagation of individual ions through the sodium channel nanotube at a femto time second time scale and Angstrom unit (10(-10) meter) spatial scale. Cilostazol-treated grafts had a thinner intima layer with less myocyte content compared with control grafts, amounting to an 82 percent decrease in total intima area compared with controls.

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We explore potential interactions between serum and dialysate magnesium levels and risks associated with dialysate potassium levels. Their main advantages compared with conventional topical corticosteroid therapy are that they are more selective in their mode of suftrex forte action, do not induce skin atrophy and are not associated with significant systemic absorption.

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A sample of 258 amblyopes supports this prediction based on the population norms for sighting dominance. More than 4 weeks later than the onset of acute pancreatitis, X-ray dosage of acyclovir in pregnancy CT scan, white blood cell count, elevation of serum FDP level, endotoxemia and fall of plasma opsonic index served as good indicators to evaluate the severity of abdominal sepsis.

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Age-associated changes in endothelial nitric oxide synthase (eNOS) expression have not been definitively linked to the pathophysiology of aortic aneurysms. clora tablets for children The findings also highlight the potential relevance of income and genetic factors in understanding state effects on the perceived reinforcing value of alcohol. Dental implant rehabilitation challenges conventional treatment with bone-anchoring techniques to provide improved retention and stability for implant-retained and supported prostheses. We purified ILDR2-containing protein complexes using tandem affinity purification tagging and identified ZNF70, a member of the Kruppel C2H2-type zinc finger protein family, as a novel ILDR2-interacting protein.

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The coupled cluster wave function is defined in terms of cluster operators for each part and these are determined from a set of coupled equations. Analysis of amino acids in hemolymph and acid hydrolysates of midguts of Anopheles dirus infected with Plasmodium cynomolgi Endoscopic ultrasound-guided fine-needle brugada pattern in a patient medicated with lamotrigine rash aspiration (EUS-FNA) has emerged as the diagnostic modality of choice for mass lesions in the pancreas. Burst mode could be elicited by step depolarization and terminates immediately after repolarization.

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The results show that cell survival pathways, such as Akt1 and p70(S6K) signaling, are suppressed after transient focal ischemia, which may contribute to the development of neuronal cell death after an ischemic insult. This is despite SAs having a higher frequency of established risk factors for the development of AF, such as ischaemic heart disease, heart failure, hypertension, and type 2 diabetes. Certain general and local factors can increase the probability of complications of septran bus reviews gastric ulcer (GU) and addition of conditionally pathogenic fungi (CPF), which requires direct examination of GU patients for fungous infections. Both clinical and radiological findings were suggestive for oesophageal atresia.

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