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We have characterized the interaction between p53(326-355) and Tat(47-57) in detail. Studies of regulatory metabolism in Moniezia expansa: glutamate, and the absence of the gamma-aminobutyrate pathway.

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This work describes a new method for determination of PNP activity in myocardial tissue using a commercially available substrate, 2-amino-6-mercapto-7-methylpurine riboside (MESG). Furthermore, the hyperalgesia was prolonged when intrathecal injections were performed. The purpose of this integrative review was to identify, review, synthesize, and analyze the existing literature addressing compassion fatigue (CF) in healthcare providers (HCPs), with careful attention to provider role and practice area.

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The aim of this work was to document the validity and usefulness of progesterone determination instead of endometrial biopsies as evidence for ovulation within a menstrual cycle. This technique was used to evaluate patients with pulmonary vascular disease. A phenotypic and genotypic study of three node-based, low-grade peripheral T-cell lymphomas: angioimmunoblastic lymphoma, T-zone lymphoma, and lymphoepithelioid lymphoma.

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Frequency response and bandwidth in low-numerical-aperture step-index plastic optical fibers. In two experiments, normatively difficult and easy Lithuanian-English word pairs were learned via test-restudy practice until each item had been correctly recalled a preassigned number of times (from 1 to 11 correct recalls). Interestingly, an experiment performed in this study revealed the proteins produced by the endophytic fungus to be capped on the nanoparticles, which led to an increase in the stability of spherical and polydispersed AgNPs with low aggregation for over 6 months.

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The incidence of colorectal cancer has been increasing in the developed world including South Korea and China. Despite its fundamental importance, little is known about how plants sense and adapt to darkness in the daily light-dark cycle, or how they adapt to unpredictable environmental stresses that compromise photosynthesis and respiration and deplete energy supplies.

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Stimuli were sets of dots presented on a computer screen, and the subjects received a food reward upon approaching the set with the larger numerosity. Does joint inflammation improve as rheumatoid vasculitis develops? For theranostic (a merging of the terms therapeutic and diagnostic) studies, GRP78-targeting AAVP particles served to deliver the human Herpes simplex virus thymidine kinase type-1 (HSVtk) gene, which has a dual function as a molecular-genetic sensor/reporter and a cell suicide-inducing transgene.

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Controlled diagnosis-oriented enhancement of automatically segmented radiographs in dentistry. Electrically controllable sudden reversals in spin and valley polarization in silicene. There are few data on the clinical implications of immunosuppressive protein expression in tumors and immune cell infiltration within the tumor microenvironment in patients with gastric cancer (GC). Measurements were acquired using Agfa, Fuji, and Kodak storage phosphor plates and it was concluded that use of the Fuji plates resulted in the highest system DQE for the ACR-2000.

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Current situation of enteral nutrition interruptions in sepsis children in pediatric intensive care unit Duodenal biopsy specimens from untreated and on gluten-free diet patients with celiac disease and controls were respectively processed for S100B and inducible nitric oxide synthase (iNOS) protein expression and nitrite production. Thus the indication should be stringent when including this procedure within the possible treatment alternatives available to the clinician.

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In the patients with erectile dysfunction, an orally administered sildenafil enhanced the penile rigidity during visual sexual stimulation. All groups were comparable as regards their basic clinical parameters. How ATP hydrolysis is coupled with LPS release from the membrane is not understood.

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Endoscopic removal of an endodontic file accidentally swallowed: clinical and legal approaches. cruzi was incubated with radiolabeled arginine, and agmatine production was inhibited in the presence of DL-alpha-difluoromethylarginine. A validated risk-of-bias tool and comparisons of the performance of different models in the same validation population were lacking. Two further observers measured in a masked and randomized order the TMH in each illumination method by using an open source software based on Java (NIH ImageJ).

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After the initial basic diagnostic tests, we decided to do a laparoscopic approach for purposes of diagnosis and treatment. If a patient with preeclampsia complains of severe dyspnea or chest pain, aortic dissection needs to be suspected and a diagnosis should not be delayed. Experimental bases for diagnosis of left bifascicular and trifascicular block. Knowing the factors that can lead to their appearance helps to establish preventative measures.

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The fourth dimension for Interactive Cardiovascular and Thoracic Surgery--on-line video brings life to publications! No significant complications or device extrusions were observed in the present series.

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TSQ (6-methoxy-8-p-toluenesulfonamido-quinoline), a common fluorescent sensor for cellular zinc, images zinc proteins. Axial Length Measurement Failure Rates With Biometers Using Swept-Source Optical Coherence Tomography Compared to Partial-Coherence Interferometry and Optical Low-Coherence Interferometry. Persyn, a member of the synuclein family, has a distinct pattern of expression in the developing nervous system. The hair erection muscle, arrector pili, is a kind of smooth muscle located in the mammalian dermis. Childhood Trauma Questionnaire (CTQ) in Brazilian samples of different age groups: findings from confirmatory factor analysis.

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The research was a source of evidence which highlighted the necessity of optimal metabolic control of the disease in the prevention of vascular complications of diabetes. During one year five patients were observed with the adult respiratory distress syndrome who were found at necropsy to have cavitated lung infarcts following bland (non-infected) pulmonary thromboembolism. We analysed a large cohort of acutely infected HIV patients starting antiretroviral therapy (ART) to determine uptake, linkage into care and time to achieve viral suppression. Stress proteins or heat shock proteins (HSPs) are ubiquitous cellular components that have long been known to act as molecular chaperones. The shaft and the proximal branches of the Y-shaped baculum form a tubular bone around a medullary cavity.

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Surgical intervention was performed and 400 mL of clear effusion were drained. Joan Mary Anderson, known to most people as Jan, was born on May 12, 1932 in Dunedin, New Zealand. The in vitro growth and differentiation of normal mammalian cells is quite different than the growth of cells derived from tumors. Epidemic spreading and risk perception in multiplex networks: A self-organized percolation method.

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Brain penetration of the oral immunomodulatory drug FTY720 and its phosphorylation in the central nervous system during experimental autoimmune encephalomyelitis: consequences for mode of action in multiple sclerosis. How the obtained results fit the in vivo occurring events is discussed. Our findings suggest that IVIg had small but detectable beneficial effects on diabetic patients with CIDP and a high degree of axonal damage.

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Abnormal movement patterns during running and single-leg squatting have been associated with a number of running-related injuries in females. Moreover, expression of the autophagosomal marker LC3-II (lipidated form of LC3) is reduced and autophagy flux is blocked in rd10 retinas before the onset of photoreceptor cell death.

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Neuronal populations involved in limbic seizure induced damage may be involved in the modulation of posterior cortical TRH levels. Phenotypic effect of mutation ts47 in the Pseudomonas aeruginosa phage transposon D3112 on expression of late phage genes Methylation-specific PCR showed a variable methylation profile of BRCA1 promoter region at different stages of embryonic development. Compound 4 shows apparent synergy with the anticancer bischloroethylnitrosourea (BCNU) in L1210 and A549 cell lines in vitro.

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Future military and civilian trauma research endeavors will seek to identify how the advances made in the past 15 years will translate toward the emerging battlefield of the future, one where forward surgical units must be lighter, smaller, and more mobile to address the changing scope of military combat operations. Implications of these results on the sequence selectivity of the two drugs are discussed. An analysis of the titles of papers submitted to the UK REF in 2014: authors, disciplines, and stylistic details.

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On a daily basis, dermasurgeons are faced with different kinds of wounds that have to be closed. PET alone, however, is the preferred modality to address functional status of the coronary circulation and response over time, if required, to medical or interventional therapy. In addition, the four HbG6PDHs responded to temperature and drought stresses in root, bark, and leaves, implicating their roles in maintaining redox balance and defending against oxidative stress.

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Evidence suggests that this type of collagen is cellular in origin and represents a transitional form of native collagen. The correlation of CD163 with VEGF expression and MVD suggests the role of CD163-positive cells in tumor angiogenesis of cHL.

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This study aimed to determine the presence and identification of aberrant mRNA transcripts of hdm2 in colorectal cancer tissues and cell lines, and determine the nature of their association with clinicopathological characteristics and survival of patients. Androgen regulation of the RNAP II protein expression was also observed in the seminal vesicles but not in the thymus and liver, indicating that androgen regulation of RNAP II protein expression appears to be limited to the male sex accessory organs.

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However, other mechanisms can be postulated that would also be consistent with some of our findings but according to which the kinetic analysis of the fluctuations would not yield true pK(a)s. Short-term administration of T-20 seems safe and provides potent inhibition of HIV replication comparable to anti-retroviral regimens approved at present. The children performed significantly better during a remission period compared with a period of active disease. MPAgenomics: an R package for multi-patient analysis of genomic markers.

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In the presence of L-NOArg, vasoactive intestinal polypeptide (3 x 10(-7) M), the nicotinic agonist dimethylphenyl piperazinium bromide (100 microM), and isoproterenol (1 microM) relaxed carbachol-induced tone. Models of human vascular disease: is there an animal of la mancha? The amount of DPC was comparatively determined with the K-SDS assay and the comet assay. The author discusses the principles of arrangement of artificial teeth in complete prostheses from the standpoint of statics. The association between blood groups and urinary tract infections in blood group antigen-secretors and nonsecretors was analyzed.

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Comorbidity of 5,10-methylenetetrahydrofolate reductase and methionine synthase gene polymorphisms and risk for neural tube defects. Also, paVICs have a greater propensity for mineralization than pmVICs. Goniometry is a reliable and objective method for determining range of motion of joints in healthy Labrador Retrievers. To evaluate the effect of electrical burns in mortality and length of stay in a critical care unit for burn patients.

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Far ultraviolet circular dichroism spectrometry of the Tyr565-Ala587 peptide suggested that the peptide undergoes conformational change upon binding heparin. Sensitivity of Candida strains isolated from bile to some antifungal antiobiotics from the polyene group We have developed a facile synthesis of degradable polyperoxides by the radical alternating copolymerization of 1,3-diene monomers with molecular oxygen at an atmospheric pressure.

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Although specific anti-neuronal antibodies such as anti-Hu may be associated with other paraneoplastic neurologic disorders, these antibodies have limited diagnostic utility with paraneoplastic cochleovestibulopathy. Orbitofrontal cortex 5-HT2A receptor mediates chronic stress-induced depressive-like behaviors and alterations of spine density and Kalirin7. Human polymorphonuclear leukocytes (PMN) produced considerable amounts of platelet-activating factor (PAF) when exposed to various concentrations of lyso-PAF, especially in the absence of albumin.

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Survival in patients treated by long-term dialysis compared with the general population. We compared regional binding values among 3 diagnostic groups and identified correlations among the regional binding values, performance in each cognitive function test, and regional atrophy.

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Astrin is required for the maintenance of sister chromatid cohesion and centrosome integrity. In this study, we use ice-templated assembly and UV-initiated cryo-polymerization to fabricate a novel kind of composite hydrogel which have both aligned macroporous structure at micrometer scale and a nacre-like layered structure at nanoscale. The preferential transformation of h-ALA to PpIX in inflammatory tissues was confirmed in human synovial biopsy tissues, where RA samples showed higher tissue concentrations of PpIX following incubation with h-ALA than did OA samples. They inhibit a wide range of viruses by blocking an early stage of the viral replication cycle. Ketamine does not inhibit inflammatory responses of cultured human endothelial cells but reduces chemotactic activation of neutrophils.

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Sensitivity and threshold analyses illustrate how the choice is affected by the probabilities of success and adverse reactions, as well as by the values placed by the patient and practitioner on treatment outcomes. Statistical analysis included delta values and areas under the curve.

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Socializing makes thick-skinned individuals: on the density of epidermal alarm substance cells in cyprinid fish, the crucian carp (Carassius carassius). We demonstrate that this method can be applied to screen expression profiles in mammary epithelial cells cultured in 3D, supported by a natural laminin-rich extracellular matrix, but requires several specific steps in the preparation of the RNA samples. The hypothesis proposed for this unusual condition could be correlated to the high rate of circulating testosterone that may have influenced and led to the development and appearance of the hair follicles in the oral mucosa. The human colon adenocarcinoma cell line HT 29 grows in culture without tight junctions (TJ). This descriptive study might be useful for further studies aiming at understanding the mechanisms by which diets rich in both fat and sugar affect the initiation of hepatic steatosis.

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These outcomes add to the growing body of literature detailing long-term effects of prenatal drug exposure, suggesting differential effects for cocaine and alcohol, and indicating that maternal age may moderate these effects. The condition is reviewed and practical management strategies are suggested. We will search the following from 1980 to March 2016: Ovid MEDLINE, CINAHL, Embase, PsycINFO, and Web of Science. There was no significant difference in the rate of re-epithelialization between eyes treated with TTX and untreated controls. NICE issues guidance on inappropriate sexual behaviour in children.

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The aims of this study were to evaluate the results of routine histopathological examination and p57(KIP2) immunoreactivity in a large series of molar and nonmolar HA in Tunisia, and to compare the accuracy of p57(KIP2) immunohistochemistry with that of nuclear DNA microsatellite polymorphism in identifying CHM. Participants were included from the survey of Midlife in the United States (MIDUS II). Recent discoveries in the area of photobiology have uncovered photoreversible changes in nuclear organization correlated with transcriptional regulation patterns that lead to de-etiolation and photoacclimation. Using Optimal Land-Use Scenarios to Assess Trade-Offs between Conservation, Development, and Social Values.

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To understand the genetic structures and variations of the superintegron (SI) in Vibrio cholerae isolated in the seventh cholera pandemic. A palladium-catalyzed, cascade 5-endo-dig cyclization-alkenylation synthesis of isoxazoles has been developed.

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MMPs are tightly regulated by the levels of active enzymes and their inhibitors, the tissue inhibitors of metalloproteinases (TIMPs). This study considers a series of potentially modifiable patient-specific and perioperative characteristics that could be considered to reduce morbidity and mortality after gastrectomy. Patterns of cognitive functioning in school-aged children with Noonan syndrome associated with variability in phenotypic expression. We sequenced the whole genomes of 474 longitudinally collected clinical isolates of Pseudomonas aeruginosa sampled from 34 children and young individuals with cystic fibrosis. The morphology of the specialized atrioventricular junctional area: the evolution of understanding.

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Carbonic anhydrase IX and renal cell carcinoma: prognosis, response to systemic therapy, and future vaccine strategies. The significance of Y chromosome microdeletion analysis in subfertile men with clinical variocele.

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Perilipin 2 and Age-Related Metabolic Diseases: A New Perspective. Mutations were defined according to the ARUP database July 1, 2016. This cross-sectional study tested the efficacy and feasibility of upper extremity task-specific training in older adults, including those with lower cognitive scores. After 2 weeks of oral erythromycin therapy she was hospitalized for acute, life threatening colchicine toxicity, with fever, diarrhea, abdominal pain, myalgia and lower extremity parasthesias and later convulsions and alopecia.

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Experimental results on the simulated and real-world data show the superiority of the proposed method in both quantitative and visual comparisons. Competing nonlinearities in quadratic nonlinear waveguide arrays. A blueprint for programming that flowed from the themes of symbolism, control, temporal rhythms, wellness through occupation, occupational role, and environment is presented. albicans were doubly labeled with fluorescein, a pH-sensitive probe, and rhodamine, a pH-insensitive probe, and incubated with human PMNs.

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The coronary artery trees from multiple phases are then aligned by a global registration using an affine transformation with quadratic terms and nonlinear simplex optimization, followed by a local registration using a cubic B-spline method with fast localized optimization. Did pre-Clovis people inhabit the Paisley Caves (and why does it matter)? TRAIL failed to kill RPE cells in vitro, but showed a strong synergistic killing effect when coincubated with protein (cycloheximide) or RNA (actinomycin D) synthesis inhibitor. Frustration relieved ferrimagnetism in novel A- and B-site-ordered quadruple perovskite. Inverse relationship between aldosterone and large artery compliance in chronically treated heart failure patients.

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Although the overall age-adjusted incidence rates for female breast cancer are higher among whites than blacks, mortality rates are higher among blacks. Differences compared with mean baseline value remained significant at the end of the follow-up period.