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Miracid is a proton pump inhibitor that inhibits secretion of gastric acid by irreversibly blocking the enzyme system of hydrogen/potassium adenosine triphosphatase, the “proton pump” of the gastric parietal cell. The drug is used in conditions, where the inhibition of gastric acid secretion may be beneficial, including aspiration syndromes, dyspepsia, gastro-oesophageal reflux disease, peptic ulcer disease, and the Zollinger–Ellison syndrome. EsMiracid that is an isomer of Miracid is also used. The dose of Miracid may need to be reduced in patients with hepatic impairment.

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A recent report suggests that genetic variations in the TNFSF15 gene contribute to the susceptibility of IBD in both Japanese and Caucasian populations. Reduced impact of alcohol use on next-day tiredness in older relative to younger adults: A role for sleep duration. Severe left ventricular (LV) systolic dysfunction is an uncommon complication of hypertrophic cardiomyopathy (HCM) that is associated with poor prognosis. Performance of multi-configurational calculations for a 1,4-bis(phenylethynyl)benzene derivative conjugated molecule.

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