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Pristinex (Ketoconazole)
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Ketoconazole

Pristinex is active against Candida spp., and Cryptococcus neoformans. However, its activity is limited compared to that of fluconazole and itraconazole. Furthermore, due to its limited penetration to cerebrospinal fluid, it is clinically ineffective in meningeal cryptococcosis. Its activity against the dimorphic moulds, Histoplasma capsulatum, Blastomyces dermatitidis, Coccidioides immitis, Sporothrix schenckii, Paracoccidioides brasiliensis, and Penicillium marneffei is favorable. However, fluconazole and itraconazole are at least as effective as Pristinex against these fungi and are safer. Thus, Pristinex remains as an alternative second-line drug for treatment of infections due to dimorphic fungi. Pristinex is not recommended for treatment of meningeal infections due to Histoplasma capsulatum, Blastomyces dermatitidis, and Coccidioides immitis due to its limited penetration to cerebrospinal fluid. Pristinex is also active against Pseudallescheria boydii and is a good alternative for treatment of pseudallescheriasis. It is also effective in pityriasis versicolor. Pristinex has practically no activity against Aspergillus spp., Fusarium spp., and zygomycetes order of fungi.

Other names for this medication:
Ketoconazole, Nizoral, Akorazol, Arcolan, Arcolane, Asquam, Biogel, Clarazole, Conazol, Daktagold, Daktarin, Dezor, Diazon, Dikoven, Eumicel, Extina, Funginoc, Fungoral, Ilgem, Kenazol, Kenazole, Ketazol, Ketokonazol, Ketolef, Ketovid, Ketozal, Liondox, Lizovag, Micoral, Micosin, Muzoral, Mycoderm, Noell, Orifungal, Oronazol, Panfungol, Perative, Phytoral, Pristinex, Tiniazol, Tinuvin, Xolegel, Yucomy, Zoloral,

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Cellular response to near-infrared femtosecond laser pulses in two-photon microscopes. Differences in granulocyte-macrophage colony-stimulating factor support the concept of the existence of an immunologic imbalance as part of the etiologic mechanisms leading to preeclampsia. Combination of quinupristin/dalfopristin and glycopeptide in severe methicillin-resistant staphylococcal infections failing previous glycopeptide regimens.

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Ramalin inhibits VCAM-1 expression and adhesion of monocyte to vascular smooth muscle cells through MAPK and PADI4-dependent NF-kB and AP-1 pathways. Separate mechanisms for magnitude and order processing in the spatial-numerical association of response codes (SNARC) effect: The strange case of musical note values. Advancements in surgical technique and systemic therapy have prompted investigation of neoadjuvant multiagent chemotherapy (NMAC) regimens with the elimination of radiation (RT).

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To date, most high-resolution studies of neurovascular coupling in small animals have been carried out in anesthetized rodents. Feral animals that have clinical endocrine disease, such as neoplasia, adrenal cortical hyperplasia, or diabetes, would exhibit clinical signs of altered behavior that would result in their removal by predators. Comparison of clinical, microscopic and rapid diagnostic test methods in the diagnosis of Plasmodium falciparum malaria in Enugu, Nigeria. The Herbert differential pitch bone screw in displaced radial head fractures.

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Two hundred twenty-nine patients with a traumatic femoral neck fracture that underwent HHA at our level-I trauma centre between 2005 and 2009 were prospectively randomized to a high-vacuum drainage or an ABT device. Photolithographic Approaches for Fabricating Highly Ordered Nanopatterned Arrays.

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The neighbour joining phylogeny tree and Principal Co-ordinate Analysis plot constructed based on Fst distances from autosomal STRs allele frequencies of the present study and other national as well as international populations show clustering of all the South Asian populations in one branch of the tree, while Middle Eastern and African populations cluster in a separate branch. Survival and non-fatal cardiac event-free rates were compared between the two groups by the Kaplan-Meier method. Intraoperative NSAIDs and higher preoperative NLR are associated with improved outcome in conservative breast cancer surgery. This study compared singletons born after cryopreservation with singletons born after fresh IVF cycles and singletons born to women in the general population. Effects of parecoxib on morphine analgesia after gynecology tumor operation: a randomized trial of parecoxib used in postsurgical pain management.

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To compare corneal thickness and epithelial thickness measurements in maps obtained using the RTVue spectral domain optical coherence tomography (SD-OCT) system and the Artemis 2 immersion arc-scanning very-high-frequency ultrasound (VHF-US) system. Nitrefazole, a 4-nitroimidazole derivative with a marked inhibitory effect on aldehyde dehydrogenase. A new tricyclic diterpenoid, named pre-segetanin (1), and two new diterpenes, named segetanin A and B (2 and 3), the latter based on the rare segetane skeleton, have been identified from the whole plant of sea spurge along with four known segetane diterpenes (4-7).

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Ultrasonographic evidence of joint thickening reversibility in acromegalic patients treated with lanreotide for 12 months. The patient sustained a central spleen rupture, liver laceration, subdural hematoma, blunt thoracic trauma with a left-sided hematothorax and right-sided pneumothorax with serial bilateral rib fractures, and an unstable fracture of the 10th thoracic vertebra. Only few cortical thymocytes were immunoreactive for PCNA, indicating low proliferative rate. Many small employers that do not offer health benefits are potential purchasers. Passive transfer of NMO-IgG and complement by continuous infusion near the optic chiasm in mice is sufficient to produce ON with characteristic NMO pathology.

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Immunostaining of rat microglia for the marker CR3 (the receptor for complement component C3) demonstrated that high concentrations of LPS (1 microg/mL) reduced the number of microglia in mixed-glial cultures. A Toolbox for Rapid Quantitative Assessment of Chronological Lifespan and Survival in Saccharomyces cerevisiae. Barks around the bole of Pinus massoniana from a pine forest near a Pb-Zn smeltery at Qujiang and a reference forest at Dinghushan natural reserve were sampled with a stainless knife at an average height of 1.5 m above the ground. Hydrological regime and salinity alter the bioavailability of Cu and Zn in wetlands.

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Surveys to determine knowledge regarding AIDS have shown in many countries, including Papua New Guinea, that a large proportion of the literate population still mistakenly believe that mosquitoes can transmit the AIDS virus from one person to another. Bidirectional transepithelial water fluxes were measured in vocal folds exposed to physiologically realistic luminal osmotic perturbations in vitro. The empirical examples are limited to the experience of patients with employer-sponsored health insurance.

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Siriraj Continuity of Care clinic (CC clinic) has been established specifically for medical students and internal medicine residency training purpose since 2006. The intervention arm will be given access to a web-based personalized diet-modification and weight-modification program. This prospective, observational study describes the pattern of commonly used prognostic markers in a hypothermia-treated cohort of cardiac arrest patients with prolonged coma. We recommend the development and implementation of focused training modules on emergency clamentin 625mg dosage of aspirin pediatric cardiology and increased communication with pediatric cardiology to improve patient safety and resource utilization.

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