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The model predicts that alleles under sex-differential selection, including sexually antagonistic alleles, will disproportionately contribute to genetic variation for disease predisposition, thereby generating substantial sexual dimorphism in the genetic architecture of complex (polygenic) diseases. Vitamin D deficiency in HIV-infected postmenopausal Hispanic and African-American women.

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Relation of distortion product otoacoustic emission with tinnitus. CT imaging allowed for co-localization of the spatial distribution of tumor hemodynamics, IFP and CT-liposome accumulation in an individual subcutaneous xenograft mouse model of breast cancer. To overcome this practical limitation of the EBI-RDF platform, we developed cMapper, a web-based tool that enables biologists to search the EBI-RDF databases in a gene-centric manner without a thorough knowledge of RDF and SPARQL. Debates about how knowledge is made and valued in evidence-based medicine (EBM) have yet to understand what discursive, social, and historical conditions allowed the EBM approach to stabilize and proliferate across western medical education.

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The wide practical uses of these polysaccharides are based on their ability to form strong gels in aqueous solutions. This study examines the regulation of the number of electromotor neurons during postnatal growth of the spinal cord in the gymnotiform teleost Sternarchus albifrons. Varicella or chickenpox is highly contagious, childhood infectious disease caused by primary infection with varicella - zoster virus from the herpes family of viruses. Histoplasma capsulatum was also cultivated in an iron-limited, chemically defined medium without the addition of chelators and it was determined that the organism could also use hemoglobin as a sole source of iron. Our findings support a link between calgranulins and atherogenesis and suggest that these mediators, and in particular S100A12, may be related to plaque instability.

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Therefore, these results suggest that miR-375 and MALAT1 form a functional axis modulating EMT in cervical cancer. Is oral pristinamycin effective for the treatment of resistant Gram-positive infections as a relay after initial parenteral antimicrobial therapy? Development of clinical trial protocols involving advanced radiation therapy techniques: the European Organisation for Research and Treatment of Cancer Radiation Oncology Group approach.

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Laboratory tests and further clinical evaluation showed hemolytic anemia, thrombocytopenia and acute renal failure. Bayesian cue integration as a developmental outcome of reward mediated learning. Synergistic Action of D-Glucose and Acetosyringone on Agrobacterium Strains for Efficient Dunaliella Transformation. Lupus anticoagulant is an antibody to phospholipid, and it is suggested that a decrease in the production of prostanoid in the endothelium causes thrombosis.

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Royal jelly (RJ), the exclusive food for queen bees, is taken as a dietary supplement because it is highly rich in nutrients. Studies with sensitive measures of renal function and/or injury are also missing in an important group where the kidney may not be at increased risk--pediatric patients. Nocardia nova causing empyema necessitatis afterlung re-transplantation: a case report. The overall goal of the integration was to increase parental involvement and exposure to the core elements of the Coping Power programme to optimize impact on families and their children.

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The term infant is ready for independent life and responds appropriately in response to changes in environmental conditions by physiological adjustments and giving signals or showing signs to his attendants. SQDG increase was also observed in field experiments with artificial irrigation in the drought region of Ukraine, at the stages of stooling and milk ripeness. Grounded Theory research method was used and data were collected from interviews, observations and archival sources. The aim of this study is to perform an updated systematic review and meta-analysis of randomized controlled trials (RCTs) evaluating the efficacy of scaling and root planing (SRP) in reducing the preterm-birth and low-birth-weight risks to analyze important subgroups and to further explore heterogeneity and bias risks in the pooled studies.

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Osteoclast dysfunction in the osteosclerotic variant of renal osteodystrophy. In the 0.1mg/m(3) group, the only animal revealing minimal granulomas exhibited a minimal increase in collagen within the granuloma. Under the class of continuous-time substitution models, the distance is commonly defined as the expected number of substitutions at any site in the sequence.

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A control coronary artery angiograph sometimes eliminates this diagnosis by detecting a fresh coronary stenosis. The loop design and the performance of the statistical analysis contribute to the quick adoption of array CGH as a routine diagnostic tool.

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Changes, if any, in the mechanical properties (MVC, half-relaxation time, fast isometric contraction, concentric contraction of the knee extensors) and flexibility of the hip joints were studied. Paired ion electrospray ionization (PIESI) mass spectrometry is an approach for analyzing ultra-low levels of anions in the positive ion mode. The brought in dead are the indicator of the three delays in getting health care. UIHC dramatically increased the influenza vaccination rate among HCWs by conducting a pandemic influenza preparedness drill. One hour and 25 min after induction of anaesthesia, a 45 min infusion of dexmedetomidine was begun, targeting a plasma concentration of 0.6 ng x ml(-1).

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The amplitudes of the respiratory adjustments to illumination were dependent on the concentration of glucose in the perfusate. Functional-anatomical prerequisites of revascularization of the femoro-popliteal arterial segment SMART: a spatially explicit bio-economic model for assessing and managing demersal fisheries, with an application to italian trawlers in the strait of sicily. During the past two decades, many acceptable new entities have been proposed, and the diagnosis and classification of these tumors have been modified.

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Near-Infrared Sentinel Lymph Node Mapping With Indocyanine Green Using the VITOM II ICG Exoscope for Open Surgery for Gynecologic Malignancies. When neurological complications are diagnosed later, they are rarely reversible.

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FspA group 2 was the largest group (67/103) consisting of 9 subgroups. The influence of the gradient elution mode and displacer salt type on the retention properties of closely related protein variants separated by high-performance anion-exchange chromatography. A serial magnetic resonance angiography demonstrated a delayed and transient narrowing of the arterial caliber, which was consistent with a focal PCA dissection with delayed vascular recanalization. Exenatide (Byetta) and insulin glargine (Lantus) are antidiabetic agents that are typically used after lack of response to an oral antidiabetic agent(s). High enzymatic activity preservation with carbon nanotubes incorporated in urease-lipid hybrid Langmuir-Blodgett films.

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paradoxus are rare species in soil and bark samples, but can be much more common in grape must. The results of this research support the novel hypothesis that some of the stress-protective effects of prebiotics and exercise are due to increases in stress-protective gut microbial species and their metabolites. The present study investigates the age variations in regional adiposity and five indices of central fat distribution among 262 adult White men resident in Peterborough, East Anglia, England. Decreased OsGH3.8 expression by RNA interference could partially restore IAA level and largely rescue the restrained growth and development phenotypes but did not affect the disease resistance of OsNPR1-OX plants.

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We undertook a qualitative analysis to identify the broader benefits of a state-wide acute stroke telemedicine service beyond the patient-clinician consultation. The objective of this study was to conduct a systematic review on the association of PA and BF in adolescence. At the first level, we utilize an autologistic model to accommodate the spatial dependence for the tooth-level binary outcomes.

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We have incorporated a standardized approach to pretreatment staging, operative technique and pathologic evaluation. A decrease in adult neurogenesis is associated with the aging process, and this decrease is closely related to memory impairment. Model predicted distributions were compared to those based on single-cell estimates obtained using a Raman microscopy method for a laboratory-scale sequencing batch reactor (SBR) system. There is always the possibility that secondary corrective procedures may be required after the initial corrective surgery. As predicted, prior repetitions of a category-matching word presented immediately after the repeated word enhanced semantic novelty, as measured with the M400 component.

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Identifying the bond responsible for the fluorescence modulation in an amyloid fibril sensor. The review is supposed to give orientation to researchers planning to enter the field, and inform which techniques help us to gain molecular information on a multi-protein complex. To develop a new kind of dental radiographic image quality indicator (IQI) for internal quality of casting metallic restoration to influence on its usage life.

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A computer-controlled syringe or peristaltic pump loaded the sample into a sample loop of the plug flow coupler, a reciprocating eight-port valve. This dose schedule caused leukopenia (less than 3,500 cells/microl) in all patients. Using outcome questionnaires as conversational tools helps practitioners focus on change at the individual item level rather than the numeric level. Neonatal and infant mortality were not affected by the type of hospital where the delivery took place.

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The CFS questionnaire is moderately reliable for most measures of physical activity. We first analyze the principles of a phase modulation scheme using MZI incorporating the triple nonlinear ring resonators, which can be fabricated and used in practical communications. Does heavy adolescent marijuana use lead to criminal involvement in adulthood?

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In this study, we developed and compared several in vitro three-dimensional systems using human nasal epithelial basal cells (HNEBCs) cultured by different methods on two types of extracellular matrices. Preoperative existence of lymph node metastasis around bowel indicates the poor response to neoadjuvant chemoradiotherapy.

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Regulatory mechanisms in the differentiation and proliferation of adipocyte and their failure in metabolic syndrome The cytoplasm with the greatest roughness correlated with the greatest light scattering suggests that redistribution and/or loss of cytoplasmic proteins contribute to cataract formation.

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We studied the symptoms, change in medical therapy, complications of surgery and effect of other factors like smoking, polyposis and asthma on endoscopy and computed tomography scan scores. This high degree of conservation suggests a functional role for the loop. AQN-1 shares extensive structural, as well as functional, similarity with two other boar sperm zona-pellucida-binding proteins, AQN-3 and AWN, which we have recently characterized.

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In the absence of substrate modulators, the phosphorylation of calmodulin and of several ras proteins by src kinase is barely detectable. Twenty-nine eyes with treatment-naive uvCME were examined before and at 5 scheduled visits within 3 months after intravitreal triamcinolone acetonide administration.

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Acute cardiorespiratory enbarrassment necessitates prompt surgical intervention. Since carbonate-hydrogencarbonate mobile phase has stronger eluting power than hydroxide or tetraborate, only dilute concentrations are needed to separate most anions. Implications for protein quality control and regulation of oligomeric enzymes are discussed.

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Thereafter, we performed plasmapheresis and steroid therapy with subsequent low-density lipoprotein adsorption, combined with the reduction of tacrolimus. We find that these systems share similar qualitative features with the majority of complex networks that have been previously studied.

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Shortly after an operation for cataracts, she developed visual hallucinations which lasted for 22 years. This review provides an update on the variety of clinical studies and case-reports investigating on CDA status as a marker for clinical outcome in cancer patients treated with nucleosidic analogs. The developed functional RGD-modified Au DENPs may be used for efficient gene therapy of different types of cancer.

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The questions of creatine penetration through the blood brain barrier and creatine transporter expression were raised. Metronomic oral cyclophosphamide (MOC) in the salvage therapy of heavily treated recurrent ovarian cancer patients: a retrospective, multicenter study. Alfacalcidol (1alpha-hydroxyvitamin D(3)) has been widely used since 1981 as a prodrug for calcitriol (1alpha,25-dihydroxyvitamin D(3)) in the treatment of hypocalcemia, chronic renal failure, hypoparathyroidism and osteoporosis. A general non-linear correlation was found between flexural and indirect tensile strength values.

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Seasonal influenza vaccines are designed to target the circulating strains, which intuitively decreases the prevalence of coinfection and the chance of pandemic emergence due to reassortment. Type 2 idiopathic macular telangiectasia (MacTel) is a progressive retinal disease associated with a slow deterioration of visual acuity, starting in the fifth to seventh decades of life. There is still a need to further assess the state of the infectious agent and to consider new, more effective regimens. This finding highlights the necessity of offering weight loss recommendations in periodic examinations to workers with exposure to occupational asthmogens.

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Mechanisms of fructose-induced hypertriglyceridaemia in the rat. Normal operation of these two widely utilized LVADs results in appreciable heat generation in vitro. The framework of a value proposition for laboratory medicine provides the core business case that drives key activities in the evolution and maintenance of high quality healthcare from research through to adoption and quality improvement in an established service. Solasodine glycoalkaloids: a novel topical therapy for basal cell carcinoma. However, limited data are available for V2O5-based anodes in lithium-ion battery design.