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Topimax (Topiramate)

Topimax is often sold under the brand name Topimax. It is an anti-convulsive drug that stands apart from all other drugs used to treat convulsions or mood disorders because it does not share the same chemical composition. Medical researchers currently do not know how Topimax works.

Other names for this medication:
Topiramate, Topamax, Epitomax, Letop, Neutop, Piramax, Talopam, Topamac, Topictal, Topigen, Topilex, Topimax, Topina, Topiramato, Topirol, Toplep,

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Acute pancreatitis (AP) is a frequent gastrointestinal disorder that causes significant morbidity, and its incidence has been progressively increasing. Herpes simplex virus (HSV) and varicella-zoster virus (VZV) are the most common cause of acute infectious encephalitis.

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All 52 Lebanese family physicians attending the annual family medicine conference in Beirut in November 2009 were asked to fill a self-administered questionnaire that included items inquiring about knowledge, beliefs, attitudes, barriers to these vaccines and their opinions regarding strategies to improve immunization rate. Better understanding of vitamin D metabolic effects and the Wnt, frizzled, secreted frizzled-related protein, Dickkopf, and low-density lipoprotein receptor-related protein gene families are promising regarding osteoarthritis genesis and therapeutics. Coagulation parameters returned to baseline by 24 hours after the last dose. Adult onset, hypopigmented solitary mastocytoma: report of two cases. Immune-Regulatory Mechanisms of Classical and Experimental Multiple Sclerosis Drugs: A Special Focus on Helminth-Derived Treatments.

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Classical medications in the treatment of inflammatory bowel diseases pylori-infected animal model and gastric cancer: recent progress and issues. The angiopoietin/Tie-2 system regulates pericyte survival and recruitment in diabetic retinopathy. Relevant hemodynamic changes of central retinal artery (CRA) and central retinal vein (CRV) were also evaluated. As a result, a rise of postprandial body temperature might not have been induced after consumption of chicken fat.

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In a recent evaluation of partnerships with the University of Kentucky HealthCare (UK HealthCare), the conceptualization of the integration management model was explored. The Hsp90-conjugated CPNT FET sensor provided a convenient and sensitive method to observe the affinity between Hsp90 to Hsp90 inhibitors in real-time. Our results support the relationship between the consumption of Herbalife products and hepatotoxicity, underscore the concern regarding the liver-related safety of this dietary supplement, and emphasize the need to establish further regulatory measures. Acute myeloid leukemia (AML) is a heterogenous disease with differential oncogene association, outcome and treatment regimens. The limit of subdiffraction imaging with fluorescent proteins currently lies at 20 nm, and therefore most protein complexes are too small (2-5 nm) to spatially resolve their individual subunits by optical means.

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In these mice, RISC treatment significantly increased the plasma level of high density lipoprotein cholesterol without affecting the level of low density lipoprotein cholesterol and triglycerides. However, the successful development of mAbs that (1) express well, (2) elicit a desirable biological effect upon binding, and (3) remain soluble and display low viscosity at high concentrations is often far more challenging. Competitive enzyme inhibition immunoassay of apolipoprotein B based on monoclonal antibody. The method appears to be of value in testing new pharmacological agents. Incidental thyroid cancers show a different pathological pattern when compared to clinically evident thyroid cancers.

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The results shed some additional light on suicidality in schizophrenia: it appears to be partly motivated by a disordered sense of self. Because the lack of CRIP1 expression in breast cancer tissue is significantly associated with a worse prognosis for patients and low endogenous CRIP1 levels in vitro increased the malignant potential of breast cancer cells, we hypothesize that CRIP1 may act as a tumor suppressor in proliferation and invasion processes.

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The physiologic effects on the cornea of dozing while wearing contact lenses were assessed by using central corneal swelling as an index in relation with lens oxygen transmissibility (Dk/t). The antioxidants used in this study were found to be effective in reducing the concentration of pyridinoline crosslinks. Cloud computing (CC) is a magnificent service-based delivery with gigantic computer processing power and data storage across connected communications channels. The chronological accumulation of mitochondrial dysfunction has been proposed as a potential mechanism in the physiological processes of aging. Hence, there remains scope for further research into this topic using alternate datasets.

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An ultrasonic method to diagnose acute testicular torsion is presented. Innovation and effectiveness: changing the scope of school nurses in New Zealand secondary schools. We have determined that high-risk E7 proteins target the proteolysis of the cellular protein tyrosine phosphatase PTPN14 and find that this activity is correlated with the retinoblastoma-independent transforming activity of E7.

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Furthermore, understanding how the pathogen detects plant phenolic compounds as a stress signal may facilitate new antifungal strategies. Combined administration of propranolol and disopyramide treatment often leads to better results in patients with atrial fibrillation refractory to only disopyramide administration.

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In this review we deal with the progress which has been made during the past 20 years in uncovering the role of PDT in the induction of the tumor-specific immune response, with special emphasis on adaptive immunity. miR-135b reverses chemoresistance of non-small cell lung cancer cells by downregulation of FZD1. Preliminary clinical results with an association of high doses of vincamine and chlordiazepoxide in subjects with recurrent depression are presented. An immunogenetic study of bullous pemphigoid with mucosal involvement in two siblings. Focusing on the Everglades National Park, we here assess the impact of changes in the hydrologic regime, as well as habitat loss, on the spatial configuration of vegetation species.

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The wear of orthopaedic prostheses results in the release of a markedly heterogeneous assortment of particulate debris, with respect to both size and shape. Ectropion is the most frequent eyelid malposition, characterized by the eversion of the margin and exposure of the conjunctiva and the cornea. Orthoptic effects on accommodation and related visual functions in an adult alternating esotrope. Role of preoptic and anterior hypothalamic cholinergic input on water intake and body temperature. Early presentation of familial paraganglioma with SDHB mutation in a 13 year old child and its mother.

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Group III was co-treated with GAR at a therapeutic dosage of 250 mg/kg body weight per day. We have characterized sequences expressed in Chinese hamster ovary (CHO) cells which are related to the intracisternal A-particle (IAP) genes of mice and Syrian hamsters.

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liberiensis shares one feature exclusively with cetaceans (the lack of layer IV across the entire cerebral cortex), other features exclusively with artiodactyls (e.g., the morphologiy of CR-immunoreactive multipolar neurons in deep cortical layers, gyrencephalic index values, hippocampus and cerebellum volumetrics), and others with at least some species of cetartiodactyls (e.g., the presence of a thick layer I, the pattern of distribution of CR-immunoreactive neurons, the presence of von Economo neurons, clustering of layer II in the occipital cortex). Witnessing peer rejection during early adolescence: neural correlates of empathy for experiences of social exclusion.

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On the other hand, it also reveals that in the same countries, control is found to be highly concentrated at the global level, namely, lying in the hands of very few important shareholders. Teledermatology is not routinely practiced in Hungary yet, however, it promises the health care system to become better, cheaper and faster, but we have to take notice on the experience and problems faced in teledermatologic applications so far, summarized in this review.

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The retention behaviour of pre-miR-29 was characterized and adjusted to achieve higher specificity in this chromatographic operation, using an ammonium sulfate stepwise gradient. To investigate the practice of obstetric ultrasound in Norway before and 2 years after a consensus conference recommending routine screening.

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The finding that the number of ADP-ribose groups on H4 equals or exceeds by one the number of acetyl groups suggests that the two modifications may share common functions. Monte Carlo softwares are widely used to understand the capabilities of electron microscopes. PET has a higher sensitivity than LS in identifying the aetiology of FUO. Changes in the cytokine network and complement parameters during open heart surgery. However, activation frequency expresses the rate of BMU appearance in a histologic slide and not the rate of origination, which is a more physiologic indicator of remodeling activity and is necessary for the development of BMU-level bone remodeling simulations.

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Hippocampal activity and connectivity between the PPC and hippocampus, on the other hand, are strongest during initial encoding, and both decline with additional encounters. A Bayesian Metropolis-coupled Markov chain Monte Carlo (MCMCMC) method for parameter estimation is developed that uses both composite and likelihood methods and is applied to the three different pairwise combinations of the human population resequence data.

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All systems gave full profiles at 100 pg of input DNA, which is within the realm of low copy number DNA analysis. In turn, uteroglobin is released into the uterine lumen in peak amounts during the receptive phase of the menstrual cycle (mid-luteal phase, days 20-23, secretion level 833.4 pg/mg total protein). The NEHEP quiz may be a good starting point for the development of a reliable knowledge assessment tool to measure and monitor glaucoma knowledge, due to its concise nature and reasonable level of difficulty. The role of exhaustion of the functional potential of the cerebral cortex in disruption of adrenal gland activity

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The disorder-driven phase inhomogeneity is correlated to strong structural distortion, giving rise to the GP. In this observational study, we analyzed the network mediating clinical tremor modulation.

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Two years after presentation of recommendations to improve the quality and efficiency of the Emergency Room (ER), we systematically examined changes in the ER with respect to volumes, triage status, and waiting times. High-throughput sequencing techniques have opened up the world of microbial diversity to scientists, and a flurry of studies in the most remote and extreme habitats on earth have begun to elucidate the key roles of microbes in ecosystems with extreme conditions. No studies have examined the effect of intermediate femoral component sizes on outcome. We construct adenovirus vectors containing the lumican gene by gateway recombinant cloning technology, which provides a basis for investigating the role of lumican gene in the pathogenesis of high myopia.

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Thermal Marangoni Convection of a Fluid Film Coating a Deformable Membrane. Thus, the need of preserved vascular pedicle to the sternum was stressed in this type of operation.

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The phenolic metabolite profile of cinnamon bark in urine is consistent with a mixture of proanthocyanidins that are depolymerized into their constitutive (epi)catechin units as well as cleaved into smaller phenolic acids during their transit along the intestinal tract, with subsequent absorption and conjugation into bioavailable metabolites. In the Djungarian hamster, photoperiodically driven seasonal variations of circulating sex steroids result in a seasonal rhythm of galanin expression in BNST neurons. Firstly, this MARS regression model captures the main perception of statistical learning theory in order to obtain a good prediction of the dependence among the main pollutants in the Oviedo urban area. What to expect from an evolutionary hypothesis for a human disease: The case of type 2 diabetes. The amide III doublet in the Raman spectra provided additional evidence of alignment in the cross-linked fibres.

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Much progress has been made in interventions to prevent HIV infection. These observations can be explained by initial attack on the cell membrane by ROS produced in the medium outside the cell and provide insight into possible uses of 5-ALA in cancer chemotherapy. Decreasing the load of specific anaerobes could reduce HIV target cell recruitment to the foreskin.

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Functional status of the stomach and liver in eczema patients (according to endoscopic and hepatographic findings) In a retrospective study, 292 Charcot feet (282 patients) undergoing reconstructive procedures in our clinic from 1996-2010 were included (93 female, 189 male, mean age 57.9 years). The effect of platelet-rich fibrin (PRF), when used along with double lateral sliding bridge flap (DLSBF), remains unknown. High levels of apolipoprotein B-containing lipoproteins, most prominently carried by low-density lipoprotein (LDL) particles, are an important risk factor for coronary heart disease.

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The impact was most significant during the middle period of the 5-year-exposure to the stressor. Furthermore, antitumor activities of YM155, in combination with bendamustine or both bendamustine and rituximab, were evaluated in mice bearing human DLBCL xenografts. The average temperature in the anterior chamber was 30 degrees C and adapted to the temperature of the irrigation fluid within seconds as soon as irrigation was started. MicroRNA-3196 is inhibited by H2AX phosphorylation and attenuates lung cancer cell apoptosis by downregulating PUMA. This higher temperature is due to heat generated internally in the cancer.

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Shoulder flexion and elbow extension decreased with FTP and were associated with increased trunk displacement. The Fas/FasL system is known, first and foremost, as a potent apoptosis activator. The authors propose a model for understanding the referral process and discuss future directions for research to guide decision making for older patients with CKD.

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With the AT1 receptor blocked, angiotensin II is available to activate the angiotensin type 2 (AT2) receptor, which mediates several potentially beneficial effects in the cardiovascular system, including vasodilation, antiproliferation, and apoptosis. During hospitalization, he developed an inflammatory plaque located on a thigh, which showed histologic features consistent with the diagnosis of interstitial granulomatous dermatitis. To test the biomarkers in patients with ECC and further elucidate the relationship of HBV or HCV infection with ECC risk, we conducted a retrospective survey on hepatitis virus markers in patients with ECC. SBS rats also demonstrated a significant three- to fourfold decrease in SMO, GIL, and PTCH mRNA, and protein levels (determined by Real-Time PCR and Western blot) compared to control animals.

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In perception, the mechanism explains the effect of stimulus strength, characterized by signal-to-noise ratio, on decision speed, accuracy and confidence. The overall reaction at steady state appears to be composed of four main reactions, eqs.

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Therefore, we set out to reliably assess cognitive functions in patients with relapsing-remitting MS (RRMS) treated with DMTs over 1 year. Synthesis of Aminoboronic Acid Derivatives from Amines and Amphoteric Boryl Carbonyl Compounds. AMPK plays a critical role in sensing metabolic and energy changes.

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For example, in virtual drug screening ROC curves are very often used to visualize the efficiency of the used application to separate active ligands from inactive molecules. The collaborative platform is provided as a Software-as-a-Service solution, supporting real time and asynchronous collaboration between users. Defining dimensions of research readiness: a conceptual model for primary care research networks. The search was limited to English language articles, and the following key words were used: Endonasal, Endoscopic, Dacryocystorhinostomy, DCR, Mucosal Flaps, between years 1970 and 2015.

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Extracorporeal Roux-en-Y anastomosis could shorten the operative time. Quality use of medicines: a new method of combining antibiotic consumption and sensitivity data--application in a Russian hospital.

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Various pen side tests, namely, lateral flow, RT-LAMP, Immunostrip tests, and so forth. The aim of this article is to give a brief outline of the various inborn errors of metabolism to consider in neonatal encephalopathy and to provide a framework for investigation and diagnosis.

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Men consumed approximately 3 times the amount of alcohol of women. T3 replacement restored normal cycles and ovary weight and increased serum E2 levels above control values, while LH levels remained below the limit of detection of the RIA.

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Profile of tuberculous meningitis with or without HIV infection and the predicators of adverse outcome. Primary and secondary hyperparathyroidism exhibit distinct pathophysiology but share certain common microscopic features.

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Usefulness of the CHADS2 Score for Determining Risk of Seizure in Patients With Atrial ketasma information security Fibrillation. The dietary pattern characterized by high intake of hydrogenated fat and sugar was shown to be positively associated with a risk of general and central obesity, however further prospective studies are required to confirm our findings. Strangulated congenital diaphragmatic hernia with partial gastric necrosis: a rare cause of abdominal pain in pregnancy.

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Optimization of conditions for high-level expression and purification of human recombinant consensus interferon (rh-cIFN) and its characterization. Recent evidence indicates that p53 suppression increased the efficiency of induced pluripotent stem cell (iPSC) generation. The effect of gamma and microwave irradiation mc domer insomnia cookies of wheat grain on development parameters of some stored grain pests. Combinatorial synthesis and biological evaluation of isoxazole-based libraries as antithrombotic agents.

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The analysis of ERG in the fellow eyes of patients with macular estructura quimica del allopurinol and alcohol hole seems clinically useful. The ascorbic levels of all subjects were low and seventeen had levels between 7-3 and 16-o mug/10-8 white blood cells. It was even possible to use (in addition to the standard methods, e.g., thin-layer chromatography and amino acid analysis) mass spectrometry without preceding gas chromatography for identification of the released PTH amino acids. Behavior of the Posterior Semicircular Canal After Dix-Hallpike Maneuver. However, mechanisms of how RNA binding proteins (RBPs) influence cellular behavior are poorly understood.

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Linear free energy relationships demonstrate a catalytic role for the flavin mononucleotide coenzyme of the type II isopentenyl diphosphate:dimethylallyl diphosphate isomerase. Having established a reliable and consistent immunization protocol of 25 micro g peptide and no PTX, the time course of histopathology was performed, which graded both cellular and structural scores individually. Enantioselective total synthesis of (-)-zampanolide, a potent microtubule-stabilizing agent. The current cross-sectional observational MR imaging study aimed to investigate the prevalence and risk factors of lumbar disc degeneration in a healthy anti inflammatory and alcohol interaction with metronidazole population and to establish the baseline data for a prospective longitudinal study. Images were processed directly without intermediate disk access.

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The sensitivity improved 100 times (to 1 pM) allowing us to detect low-abundance miRNAs in an RNA extract. Special procedures were developed for the odyne pronunciation of biblical names definitions of the nasion and sella reference points on the radiographs in the early stages of fetal development.

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One aim was to determine whether the diagnostic accuracy of cozole medication reconciliation these instruments could be improved for predicting unplanned emergency department (ED) readmission following ED discharge. The drug parallel features of the same compounds were also assessed in silico. The complexity of the biomass processing is recognized through the analysis of the different stages involved in the conversion of lignocellulosic complex into fermentable sugars.

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